Interspecies differences in the substance P- and vasoactive intestinal polypeptide-like immunoreactivities in the olfactory bulb of Salmo gairdneri and Barbus meridionalis.

Alonso JR, Coveñas R, Lara J, de León M, Arévalo R, Aijón J

Journal of neuroscience research1 Jan 1990Cited by 5 (Europe PMC)

PMID1690815DOI10.1002/jnr.490250113PepBankPUB-01690815

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In the rainbow trout olfactory bulb, the VIP antiserum gave very strong immunostaining in the olfactory nerve fiber layer.
In plain wordsIn rainbow trout, the body's own VIP showed very strongly in the nerve fibers of the olfactory bulb.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableVIP-like immunostaining in the olfactory nerve fiber layer of rainbow trout
Study
rainbow troutn: not reported in source
olfactory bulb
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
the VIP antiserum used displayed very strong immunostaining in the olfactory nerve fiber layer of Salmo gairdneri, whereas those fibers in Barbus meridionalis showed no immunoreactivity.
1 context sentence(design, population, supporting numbers)
Summary · context
The distribution of substance P-like (SP) and vasoactive intestinal polypeptide-like (VIP) structures was studied using an indirect immunoperoxidase technique in the mediterranean barbel Barbus meridionalis and in the rainbow trout Salmo gairdneri.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0169081501
02AnimalEndogenous levelAnimal study (in vivo)Other
In the mediterranean barbel olfactory bulb, olfactory nerve fibers showed no VIP immunoreactivity.
In plain wordsIn barbel fish, the body's own VIP was not detected in the nerve fibers of the olfactory bulb.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
No significant changeVIP-like immunostaining in the olfactory nerve fibers of mediterranean barbel
Study
mediterranean barbeln: not reported in source
olfactory bulb
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
whereas those fibers in Barbus meridionalis showed no immunoreactivity.
1 context sentence(design, population, supporting numbers)
Summary · context
The distribution of substance P-like (SP) and vasoactive intestinal polypeptide-like (VIP) structures was studied using an indirect immunoperoxidase technique in the mediterranean barbel Barbus meridionalis and in the rainbow trout Salmo gairdneri.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0169081502
03AnimalEndogenous levelAnimal study (in vivo)Other
VIP immunoreactivity was confined to the olfactory fibers, in both the olfactory nerve and the olfactory bulb.
In plain wordsIn fish, the body's own VIP was found only in the olfactory nerve fibers.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableLocation of VIP immunoreactivity
Study
freshwater teleost fishn: not reported in source
olfactory bulb
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
The VIP immunoreactivity was confined to the olfactory fibers, both in the olfactory nerve and the olfactory bulb.
1 context sentence(design, population, supporting numbers)
Summary · context
The distribution of substance P-like (SP) and vasoactive intestinal polypeptide-like (VIP) structures was studied using an indirect immunoperoxidase technique in the mediterranean barbel Barbus meridionalis and in the rainbow trout Salmo gairdneri.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0169081503
04AnimalEndogenous levelAnimal study (in vivo)Other
VIP immunostaining disappeared after chemical lesion of the olfactory mucosa.
In plain wordsIn fish, the body's own VIP staining disappeared after the olfactory mucosa was damaged by chemicals.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
DecreaseVIP immunostaining after chemical lesion of the olfactory mucosa
Study
freshwater teleost fishn: not reported in source
olfactory mucosa lesion
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
The positive immunostaining disappeared after chemical lesion of the olfactory mucosa.
1 context sentence(design, population, supporting numbers)
Summary · context
The distribution of substance P-like (SP) and vasoactive intestinal polypeptide-like (VIP) structures was studied using an indirect immunoperoxidase technique in the mediterranean barbel Barbus meridionalis and in the rainbow trout Salmo gairdneri.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0169081504

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
12 Oct 2026, 12:58 UTC
Study results updated
Version 1
9 Oct 2026, 12:41 UTC
First added · source update from Europe PMC

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