In human T lymphocytes, synthetic thymosin-like peptides 1-3 did not significantly enhance RNA synthesis compared with thymosin alpha‑1, thymosin alpha‑1 (15-28) and thymopentin.
In plain wordsIn lab tests, the three new peptides did not boost T cell activation compared with thymosin alpha‑1, its fragment and thymopentin.
- Peptide
- Thymosin alpha-1
- Outcome
- No significant changeT lymphocyte activation (RNA synthesis) by synthetic thymosin-like peptides 1-3
- Study
humann: not reported in source
Human T lymphocytes- Comparator
- Thymosin alpha 1, thymosin alpha 1 (15-28) and thymopentin
- Outcome group
- Immune response · Immune and inflammation
Source sentences
In comparison to thymosin alpha 1, thymosin alpha 1 (15-28), and thymopentin, peptides 1-3 did not show significant enhancement of these processes.
1 context sentence(design, population, supporting numbers)
The ability of peptides 1-3 to enhance the activation (RNA synthesis) and proliferation (DNA synthesis) of human T lymphocytes was determined.
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.