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Study · Animal study (in vivo) · rat · 1991

3 results

[Effects of dermorphin on processes of cell division in the corneal and tongue epithelium of white rats].

Radivoz MI, Mel'nik EI, Timoshin SS, Deĭgin VI

Biulleten' eksperimental'noi biologii i meditsiny1 Aug 1991Cited by 1 (Europe PMC)

PMID1686190 (opens in a new tab)PepBankPUB-01686190
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In white rats, dermorphin suppressed epithelial DNA synthesis at 4 and 24 hours after injection.

    In plain wordsIn rats, dermorphin reduced epithelial DNA synthesis at 4 and 24 hours after injection.

    Peptide
    Dermorphin
    Outcome
    DecreaseDNA synthesis
    Study

    ratn: not reported in source

    White rats with corneal and tongue epithelial assessment
    Outcome group
    Cell proliferation and differentiation · Whole body
    Studied dose
    10 micrograms/kgAs given in this study (rat).

    Source sentences

    Summary
    The injection of dermorphin in dose 10 micrograms/kg compressed the DNA-synthesis in 4 and 24 hours since the moment of administration.
    1 context sentence
    Summary · context
    The character of dermorphin influence on cell division in corneal and tongue epithelium of white rats was studied by the method of radioautography with 3H-thymidine.
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In white rats, the epithelial mitotic index increased 4 hours after dermorphin injection.

    In plain wordsIn rats, the epithelial cell division index increased 4 hours after dermorphin injection.

    Peptide
    Dermorphin
    Outcome
    IncreaseMitotic index at 4 hours
    Study

    ratn: not reported in source

    White rats with corneal and tongue epithelial assessment
    Outcome group
    Cell proliferation and differentiation · Whole body
    Studied dose
    10 micrograms/kgAs given in this study (rat).

    Source sentences

    Summary
    The mitotic index increased in 4 hours and decreased in 24 hours.
    2 context sentences
    Summary · context
    The injection of dermorphin in dose 10 micrograms/kg compressed the DNA-synthesis in 4 and 24 hours since the moment of administration.
    Summary · context
    The character of dermorphin influence on cell division in corneal and tongue epithelium of white rats was studied by the method of radioautography with 3H-thymidine.
  3. 03AnimalAnimal study (in vivo)Activity measurement

    In white rats, the epithelial mitotic index decreased 24 hours after dermorphin injection.

    In plain wordsIn rats, the epithelial cell division index decreased 24 hours after dermorphin injection.

    Peptide
    Dermorphin
    Outcome
    DecreaseMitotic index at 24 hours
    Study

    ratn: not reported in source

    White rats with corneal and tongue epithelial assessment
    Outcome group
    Cell proliferation and differentiation · Whole body
    Studied dose
    10 micrograms/kgAs given in this study (rat).

    Source sentences

    Summary
    The mitotic index increased in 4 hours and decreased in 24 hours.
    2 context sentences
    Summary · context
    The injection of dermorphin in dose 10 micrograms/kg compressed the DNA-synthesis in 4 and 24 hours since the moment of administration.
    Summary · context
    The character of dermorphin influence on cell division in corneal and tongue epithelium of white rats was studied by the method of radioautography with 3H-thymidine.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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