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Study · Animal study (in vivo) · 1991

3 results

[Antistressor effect of delta-sleep-inducing peptide in hypokinetic stress].

Mendzheritskiĭ AM, Makletsova MG, Uskova NI, Choraian IO, Mikhaleva II

Ukrainskii biokhimicheskii zhurnal (1978)1 Jan 1991Cited by 2 (Europe PMC)

PMID1674176 (opens in a new tab)PepBankPUB-01674176

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In animals under hypokinetic stress, DSIP injection normalized the levels of neurotransmitter amino acids.

    In plain wordsIn stressed animals, DSIP injection brought neurotransmitter amino acid levels back to normal.

    Outcome
    Direction not reportedNeurotransmitter amino acid levels in hypokinetic stress
    Study

    n: not reported in source

    Outcome group
    Stress hormones · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The injection of DSIP normalized the level of neurotransmitter amino acids.
    2 context sentences
    Summary · context
    The influence of DSIP injection on the levels of neurotransmitters during hypokinetic stress was studied.
    Summary · context
    It was shown that hypokinesia produced considerable changes in the levels of GABA glutamate, aspartate and homocarnosine.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In animals under hypokinetic stress, DSIP reduced the stress-induced changes in the activity of enzymes of GABA metabolism.

    In plain wordsIn stressed animals, DSIP reduced stress-related changes in the activity of GABA-handling enzymes.

    Outcome
    Direction not reportedActivity of GABA metabolism enzymes in hypokinetic stress
    Study

    n: not reported in source

    Outcome group
    Stress hormones · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of DSIP also reduced stress-induced changes in the activity of enzymes of GABA metabolism.
    2 context sentences
    Summary · context
    The influence of DSIP injection on the levels of neurotransmitters during hypokinetic stress was studied.
    Summary · context
    It was shown that hypokinesia produced considerable changes in the levels of GABA glutamate, aspartate and homocarnosine.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In animals under hypokinetic stress, DSIP normalized the POL of lipids in brain.

    In plain wordsIn stressed animals, DSIP brought a brain lipid oxidation measure back to normal.

    Outcome
    Direction not reportedLipid peroxidation (POL) in brain in hypokinetic stress
    Study

    n: not reported in source

    Outcome group
    Stress hormones · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Stress protective effect of DSIP was also demonstrated by normalising of the POL of lipids in brain.
    2 context sentences
    Summary · context
    The influence of DSIP injection on the levels of neurotransmitters during hypokinetic stress was studied.
    Summary · context
    It was shown that hypokinesia produced considerable changes in the levels of GABA glutamate, aspartate and homocarnosine.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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