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Study · Ex vivo tissue · rat · 1991

3 results

Effect of ethanol and DSIP on the 36Cl-flux in synaptosomal vesicles.

Yukhananov R, Rebrov I, Tennila T, Maisky A

Molecular and chemical neuropathology1 Dec 1991Cited by 2 (Europe PMC)

PMID1666953 (opens in a new tab)DOI10.1007/bf03161062 (opens in a new tab)PepBankPUB-01666953
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In rat brain cortex synaptosomal vesicles, DSIP, like diazepam and ethanol, activated muscimol-stimulated 36Cl- uptake.

    In plain wordsIn lab tests on rat brain cells, DSIP increased chloride uptake, as diazepam and ethanol did.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseMuscimol-stimulated 36Cl- uptake
    Study

    ratn: not reported in source

    Rat brain cortex synaptosomal vesicles
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was found that DSIP, like diazepam and ethanol, activates muscimol-stimulated 36Cl- uptake in the rat brain cortex
    1 context sentence
    Summary · context
    Delta-sleep-inducing peptide (DSIP) is an endogenous substance that regulates the response of the organism to stress.
  2. 02LabEx vivo tissueActivity measurement

    In rat brain cortex synaptosomal vesicles, DSIP partially counteracted the stimulatory action of ethanol on 36Cl- uptake.

    In plain wordsIn lab tests on rat brain cells, DSIP partly reduced the chloride uptake that ethanol caused.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseEthanol-stimulated 36Cl- uptake
    Study

    ratn: not reported in source

    Rat brain cortex synaptosomal vesicles
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    partially counteracts the stimulatory action of ethanol on this process.
    1 context sentence
    Summary · context
    Delta-sleep-inducing peptide (DSIP) is an endogenous substance that regulates the response of the organism to stress.
  3. 03LabEx vivo tissueMechanism

    In rat brain cortex synaptosomal vesicles, the DSIP effect disappeared when the incubation temperature was lowered.

    In plain wordsIn lab tests on rat brain cells, the DSIP effect disappeared at a lower temperature.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableTemperature dependence of the DSIP effect
    Study

    ratn: not reported in source

    Rat brain cortex synaptosomal vesicles
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The effect of peptide disappears at the lowering of the incubation temperature.
    1 context sentence
    Summary · context
    Delta-sleep-inducing peptide (DSIP) is an endogenous substance that regulates the response of the organism to stress.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

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