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Study · Ex vivo tissue · chicken · 1991

2 results

Molecular characterization and peptide specificity of two vasoactive intestinal peptide (VIP) binding sites in the chicken pineal.

Meunier AC, Voisin P, Van Camp G, Cenatiempo Y, Muller JM

Neuropeptides1 May 1991Cited by 11 (Europe PMC)

PMID1653910 (opens in a new tab)DOI10.1016/0143-4179(91)90066-r (opens in a new tab)PepBankPUB-01653910
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    Chicken pineal membranes express high affinity receptors for VIP, shown by competitive displacement of radioiodinated VIP by native VIP.

    In plain wordsIn lab tests on chicken pineal gland membranes, VIP bound to receptors that hold it tightly.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableHigh affinity VIP binding in chicken pineal membranes
    Study

    chickenn: not reported in source

    Chicken pineal membranes
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Here we report that chicken pineal membranes express high affinity receptors for Vasoactive Intestinal Peptide (VIP), as revealed by competitive displacement analysis of [3-iodotyrosyl-125I]-VIP by native VIP.
  2. 02LabEx vivo tissueActivity measurement

    Cross-linking of radioiodinated VIP to chicken pineal membranes revealed two polypeptides, P1 (Mr 57,000) and P2 (Mr 70,000), with similar labelling intensity.

    In plain wordsIn lab tests on chicken pineal gland membranes, VIP attached to two different proteins of different sizes.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableMolecular weight of VIP binding components
    Study

    chickenn: not reported in source

    Chicken pineal membranes
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Sodium dodecyl sulfate electrophoresis after solubilization of the cross-linked membranes, reveals the existence of two polypeptides, P1 and P2, with a similar labelling intensity and apparent molecular weights of Mr = 57,000 and Mr = 70,000 respectively.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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