Skip to content

Study · Ex vivo tissue · rat · 1991

1 result

Serotonin release in the rat brain cortex is inhibited by neuropeptide Y but not affected by ACTH1-24, angiotensin II, bradykinin and delta-sleep-inducing peptide.

Schlicker E, Gross G, Fink K, Glaser T, Göthert M

Naunyn-Schmiedeberg's archives of pharmacology1 Feb 1991Cited by 9 (Europe PMC)

PMID1648670 (opens in a new tab)DOI10.1007/bf00168597 (opens in a new tab)PepBankPUB-01648670
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In superfused rat brain cortex slices, delta sleep-inducing peptide did not change the electrically evoked 3H (serotonin) overflow.

    In plain wordsIn lab tests on rat brain slices, DSIP did not change the release of serotonin.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeElectrically evoked 3H (serotonin) overflow
    Study

    ratn: not reported in source

    Superfused rat brain cortex slices preincubated with 3H-serotonin
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The electrically (3 Hz) evoked 3H overflow was inhibited by PYY, NPY and pancreatic polypeptide (decreasing order of potency), but not affected by ACTH1-24, angiotensin II, bradykinin and delta-sleep-inducing peptide.
    1 context sentence
    Summary · context
    The effects of neuropeptide Y (NPY), peptide YY (PYY), pancreatic polypeptide and of another four peptides on the electrically evoked 3H overflow were studied in superfused rat brain cortex slices preincubated with 3H-serotonin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.