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Study · Animal study (in vivo) · 1992

3 results

[Morphometric evidence of activation of axo-somatic synapses during administration of delta sleep-inducing peptide].

Mendzheritskiĭ AM, Kuraev GA, Mikhaleva II, Povilaĭtite PE

Biulleten' eksperimental'noi biologii i meditsiny1 Feb 1992

PMID1611076 (opens in a new tab)DOI10.1007/bf00791500 (opens in a new tab)PepBankPUB-01611076
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    After a single intraperitoneal DSIP dose, the mean plasmalemma length of active synapse zones on neurone bodies increased in neocortex layers III-V.

    In plain wordsIn animals, one injection of DSIP lengthened active contact zones on nerve-cell bodies in the brain cortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreasePlasmalemma length of active synapse zones on neurone bodies
    Study

    n: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · intraperitoneal · single administrationAs given in this study.

    Source sentences

    Summary
    This is evident from an increase in the mean plasmalemma length, that in the active synapse zones on neurone bodies and width of the synaptic cleft, this being induced by a single intraperitoneal administration of delta-sleep-inducing peptide.
  2. 02AnimalAnimal study (in vivo)Mechanism

    After a single intraperitoneal DSIP dose, the width of the synaptic cleft of axosomatic synapses increased in neocortex layers III-V.

    In plain wordsIn animals, one injection of DSIP widened the gap of nerve-cell contacts in the brain cortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseWidth of the synaptic cleft
    Study

    n: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · intraperitoneal · single administrationAs given in this study.

    Source sentences

    Summary
    This is evident from an increase in the mean plasmalemma length, that in the active synapse zones on neurone bodies and width of the synaptic cleft, this being induced by a single intraperitoneal administration of delta-sleep-inducing peptide.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In animals given DSIP, activation of axosomatic synapses correlated with elevated GABA levels in the cerebral hemispheres cortex.

    In plain wordsIn animals given DSIP, more active nerve-cell contacts were linked to higher GABA levels in the brain cortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseGABA levels in cerebral hemispheres cortex
    Study

    n: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · intraperitoneal · single administrationAs given in this study.

    Source sentences

    Summary
    The activation of the axosomatic synapses correlates with elevated GABA levels in the cerebral hemispheres cortex.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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