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Study · Non-randomized trial · n = 10 · 1992

1 result

Potential role for medroxyprogesterone acetate as an adjunct to goserelin (Zoladex) in the medical management of uterine fibroids.

West CP, Lumsden MA, Hillier H, Sweeting V, Baird DT

Human reproduction (Oxford, England)1 Mar 1992Cited by 22 (Europe PMC)

PMID1534089 (opens in a new tab)DOI10.1093/oxfordjournals.humrep.a137643 (opens in a new tab)PepBankPUB-01534089
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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In women with symptomatic fibroids, uterine volume fell by 39% after three months of goserelin alone.

    In plain wordsIn women with symptomatic fibroids, uterine volume fell by 39% after three months of goserelin alone.

    Peptide
    Goserelin
    Outcome
    DecreaseUterine volume at three months
    Study

    n = 10

    Outcome group
    Uterine Volume · Reproductive and sexual health
    Studied dose
    Dose not stated · 3 monthsAs given in this study (human).

    Measurements

    Baseline uterine volume
    557 cm3
    goserelin-alone initial period
    Uterine volume reduction
    39%
    after 3 months

    Source sentences

    Summary
    The mean uterine volume (557 cm3) fell by 39% after 3 months with no significant regrowth by 6 months.
    1 context sentence
    Summary · context
    The other 10 women received goserelin alone for the initial 3 months, followed by combined treatment for 3 months.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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