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Study · Not a test of the peptide alone · 1992

5 results

Production and immunohistochemical application of monoclonal antibodies against delta sleep-inducing peptide.

Charnay Y, Golaz J, Vallet PG, Bouras C

Journal of chemical neuroanatomy1 Nov 1992Cited by 3 (Europe PMC)

PMID1476667 (opens in a new tab)DOI10.1016/0891-0618(92)90005-b (opens in a new tab)PepBankPUB-01476667
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 01AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Other

    The monoclonal antibodies gave strong immunolabelling of a large population of fibres and terminal-like structures in rat median eminence sections.

    In plain wordsIn rat brain sections, the antibodies strongly labelled many nerve fibres and endings in the median eminence.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableImmunolabelling of rat median eminence
    Study

    ratn: not reported in source

    median eminence sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Application of these monoclonal antibodies to rat median eminence sections gave a strong immunolabelling of a large population of fibres and terminal-like structures, mainly localized through the lateral areas.
    1 context sentence
    Summary · context
    Monoclonal antibodies were produced following immunization of rats with delta sleep-including peptide (DSIP).

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  2. 02AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Other

    Incubation of mouse, hamster and gerbil median eminence sections with the anti-DSIP monoclonal antibodies gave no immunoreaction.

    In plain wordsIn mouse, hamster and gerbil brain sections, the anti-DSIP antibodies did not label the median eminence.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableImmunolabelling of median eminence in mouse, hamster and gerbil
    Study

    mouse, hamster, gerbiln: not reported in source

    median eminence sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Although numerous LHRH-immunoreactive neuronal elements were also easily demonstrated in the median eminence of the mouse, the hamster and the gerbil species, incubation of sections with monoclonal antibodies to DSIP failed to give any immunoreaction.
    1 context sentence
    Summary · context
    Monoclonal antibodies were produced following immunization of rats with delta sleep-including peptide (DSIP).

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  3. 03AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Other

    In rat median eminence, elution-restaining with an anti-DSIP monoclonal antibody and an anti-LHRH antiserum showed that the two immunoreactivity patterns overlapped almost completely.

    In plain wordsIn rat brain sections, the DSIP antibody and an LHRH antiserum labelled almost the same structures in the median eminence.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableOverlap of DSIP and LHRH immunoreactivity in rat median eminence
    Study

    ratn: not reported in source

    median eminence sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Elution-restaining experiments using a monoclonal antibody to DSIP and a polyclonal antiserum to luteinizing hormone-releasing hormone (LHRH) showed that the patterns of immunoreactivity respectively visualized overlap almost completely.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  4. 04LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    Supernatants of six stable hybridoma clones reacted with DSIP in a solid-phase immunoassay.

    In plain wordsIn lab tests, antibodies from six cell clones bound to DSIP.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableReactivity of hybridoma supernatants with DSIP
    Study

    ratn: not reported in source

    solid-phase dot-immunobinding assay
    Outcome group
    Endogenous peptide levels · Pharmacology

    Source sentences

    Summary
    The supernatants of six stable producer clones were found to react with DSIP.
    2 context sentences
    Summary · context
    The supernatants of hybridomas were screened on a solid-phase immunoassay using dot-immunobinding of DSIP and some DSIP fragments.
    Summary · context
    Monoclonal antibodies were produced following immunization of rats with delta sleep-including peptide (DSIP).

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  5. 05LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    All the monoclonal antibodies recognized epitopes in the penta carboxy-terminal region of DSIP (DSIP5-9).

    In plain wordsIn lab tests, all the antibodies bound to the carboxy-terminal end of DSIP.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableEpitope region recognized by the antibodies
    Study

    ratn: not reported in source

    solid-phase dot-immunobinding assay
    Outcome group
    Endogenous peptide levels · Pharmacology

    Source sentences

    Summary
    From this procedure it was also deduced that all these monoclonal antibodies recognized epitope(s) of the penta carboxy-terminal region of DSIP (DSIP5-9).
    1 context sentence
    Summary · context
    Monoclonal antibodies were produced following immunization of rats with delta sleep-including peptide (DSIP).

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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