Immunohistochemical localization of delta sleep-inducing peptide (DSIP) in the brain and pituitary of the cartilaginous fish Scyliorhinus canicula.

Vallarino M, Feuilloley M, Yon L, Charnay Y, Vaudry H

Peptides1 Jul 1992Cited by 5 (Europe PMC)

PMID1437707DOI10.1016/0196-9781(92)90168-3PepBankPUB-01437707

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In the cartilaginous fish Scyliorhinus canicula, DSIP-like immunoreactive cell bodies were mainly in the nucleus lateralis tuberis of the hypothalamus.
In plain wordsIn dogfish, natural DSIP-like material was found mainly in cells of one hypothalamic nucleus.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
Not applicableDSIP-like immunoreactive cell bodies in the hypothalamus
Study
dogfish (Scyliorhinus canicula)n: not reported in source
brain and pituitary tissue sections
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
Delta sleep-inducing peptide-like immunoreactive cell bodies were mainly observed in the nucleus lateralis tuberis of the hypothalamus.
1 context sentence(design, population, supporting numbers)
Summary · context
The distribution of delta sleep-inducing peptide (DSIP) in the brain and pituitary of the cartilaginous fish Scyliorhinus canicula was investigated using the indirect immunofluorescence technique.
This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0143770701
02AnimalEndogenous levelAnimal study (in vivo)Other
In the fish pituitary, numerous DSIP-like immunoreactive cells were in the median lobe of the pars distalis.
In plain wordsIn dogfish, natural DSIP-like material was found in many cells of the middle lobe of the pituitary.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
Not applicableDSIP-like immunoreactive cells in the pituitary
Study
dogfish (Scyliorhinus canicula)n: not reported in source
brain and pituitary tissue sections
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
In the pituitary, numerous DSIP-like immunoreactive cells were detected in the median lobe of the pars distalis.
1 context sentence(design, population, supporting numbers)
Summary · context
The distribution of delta sleep-inducing peptide (DSIP) in the brain and pituitary of the cartilaginous fish Scyliorhinus canicula was investigated using the indirect immunofluorescence technique.
This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0143770702
03AnimalEndogenous levelAnimal study (in vivo)Mechanism
In the fish pituitary median lobe, DSIP- and MCH-like immunoreactive cells overlapped, so the two neuropeptides are stored in the same cells.
In plain wordsIn dogfish, natural DSIP-like material and MCH were stored in the same cells of the pituitary.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
Not applicableColocalization of DSIP and MCH in pituitary cells
Study
dogfish (Scyliorhinus canicula)n: not reported in source
brain and pituitary tissue sections
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
Comparison of the distribution of DSIP- and MCH-like immunoreactive cells revealed that the two neuropeptides are stored in the same cells of the median lobe of the pituitary.
2 context sentences(design, population, supporting numbers)
Summary · context
In particular, a high concentration of cells was seen in the dorsal wall of the median lobe, an area which is known to contain melanin-concentrating hormone (MCH)-producing cells.
Summary · context
The distribution of delta sleep-inducing peptide (DSIP) in the brain and pituitary of the cartilaginous fish Scyliorhinus canicula was investigated using the indirect immunofluorescence technique.
This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0143770703
04AnimalEndogenous levelAnimal study (in vivo)Other
In the cartilaginous fish Scyliorhinus canicula, a dense network of DSIP-positive fibers was seen throughout the midcaudal hypothalamus, the lateral lobes and the posterior lobe.
In plain wordsIn dogfish, natural DSIP-like material was found in a dense network of nerve fibres in the hypothalamus.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
Not applicableDSIP-positive fibres in the hypothalamus
Study
dogfish (Scyliorhinus canicula)n: not reported in source
brain and pituitary tissue sections
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
A dense network of DSIP-positive fibers was seen throughout the midcaudal hypothalamus, the lateral lobes, and the posterior lobe.
This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0143770704

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
10 Oct 2026, 09:43 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

PepBank is a research reference. Talk to a doctor before you use any peptide.