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Study · Measured the body's own peptide · 1992

2 results

Neurohypophysial vasopressin and oxytocin as influenced by (6R)-5,6,7,8-tetrahydro-alpha-biopterin in euhydrated and dehydrated rats.

Ciosek J, Guzek JW, Orłowska-Majdak M

Biological chemistry Hoppe-Seyler1 Oct 1992Cited by 7 (Europe PMC)

PMID1418678 (opens in a new tab)DOI10.1515/bchm3.1992.373.2.1079 (opens in a new tab)PepBankPUB-01418678
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In euhydrated rats, chronic BH4 treatment did not decrease neurohypophysial content of the body's own oxytocin.

    In plain wordsIn rats with normal water intake, BH4 did not lower the body's own oxytocin stored in the pituitary gland.

    Peptide
    Oxytocin
    Outcome
    No significant changeNeurohypophysial oxytocin content after chronic BH4 in euhydrated rats
    Study

    ratn: not reported in source

    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Chronic treatment with BH4, administered to not dehydrated animals, was followed by a significant decrease of neurohypophysial vasopressin, but not of neurohypophysial oxytocin.
    1 context sentence
    Summary · context
    Experiments were performed to test a possible role of (6R)-5,6,7,8-tetrahydro-alpha-biopterin dihydrochloride (BH4) in the neurohypophysial vasopressin and oxytocin content in euhydrated and dehydrated rats.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In dehydrated rats given BH4 at the same time, the decrease of neurohypophysial content of the body's own oxytocin was distinctly less marked.

    In plain wordsIn dehydrated rats, BH4 lessened the fall in the body's own oxytocin stored in the pituitary gland.

    Peptide
    Oxytocin
    Outcome
    IncreaseNeurohypophysial oxytocin content in dehydrated rats given BH4
    Study

    ratn: not reported in source

    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    In rats dehydrated and treated simultaneously with BH4 the decrease of neurohypophysial oxytocin content was distinctly less marked.
    1 context sentence
    Summary · context
    Experiments were performed to test a possible role of (6R)-5,6,7,8-tetrahydro-alpha-biopterin dihydrochloride (BH4) in the neurohypophysial vasopressin and oxytocin content in euhydrated and dehydrated rats.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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