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Study · Measured the body's own peptide · 1992

1 result

The circadian rhythm of atrial natriuretic peptide, vasoactive intestinal peptide, beta-endorphin and cortisol in healthy young and elderly subjects.

Cugini P, Lucia P, Di Palma L, Re M, Canova R, Gasbarrone L, Cianetti A

Clinical autonomic research : official journal of the Clinical Autonomic Research Society1 Apr 1992Cited by 5 (Europe PMC)

PMID1386266 (opens in a new tab)DOI10.1007/bf01819666 (opens in a new tab)PepBankPUB-01386266
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In healthy elderly subjects aged 65-75 years, the mesor of the body's own vasoactive intestinal peptide was lower than in young subjects.

    In plain wordsIn healthy older adults, the body's own VIP followed a lower daily level than in young adults.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseVIP circadian mesor in elderly subjects
    Study

    n: not reported in source

    Comparator
    Young subjects
    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    In elderly subjects oscillation (mesor) of atrial nutriuretic peptide was higher, while that of vasoactive intestinal peptide and beta-endorphins was lower.
    1 context sentence
    Summary · context
    We evaluated the circadian rhythm of these peptides and hormones in healthy subjects who were young (between 20-25 years) or elderly (between 65-75 years).

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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