Skip to content

Study · Measured the body's own peptide · 1992

3 results

HPA-related CSF neuropeptides in suicide attempters.

Träskman-Bendz L, Ekman R, Regnéll G, Ohman R

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology1 Jun 1992Cited by 44 (Europe PMC)

PMID1378770 (opens in a new tab)DOI10.1016/0924-977x(92)90018-4 (opens in a new tab)PepBankPUB-01378770
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In suicide attempters, no significant relationship was found between cerebrospinal fluid neuropeptides, including the body's own DSIP, and CSF 5-HIAA.

    In plain wordsIn people who had attempted suicide, natural DSIP and other spinal fluid neuropeptides were not linked to the serotonin breakdown product 5-HIAA.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeCSF neuropeptides and CSF 5-HIAA
    Study

    n = 44

    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    We found no significant relationships between neuropeptides and CSF 5-HIAA.
    2 context sentences
    Summary · context
    The neuropeptides were compared with the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) in CSF and with post-dexamethasone plasma cortisol.
    Summary · context
    Corticotropin-releasing hormone (CRH), somatostatin (SOM), delta-sleep-inducing peptide (DSIP), neuropeptide Y (NPY), beta-endorphin (beta-END), and vasopressin (AVP), which are regarded as being involved in the HPA-regulation were investigated in lumbar CSF of 44 suicide attempters.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In suicide attempters, cerebrospinal fluid neuropeptide levels, including the body's own DSIP, did not differ between men and women.

    In plain wordsIn people who had attempted suicide, natural DSIP and other spinal fluid neuropeptides did not differ between men and women.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeCSF neuropeptides by sex
    Study

    n = 44

    Comparator
    Women
    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    There were no differences between men and women.
    1 context sentence
    Summary · context
    Corticotropin-releasing hormone (CRH), somatostatin (SOM), delta-sleep-inducing peptide (DSIP), neuropeptide Y (NPY), beta-endorphin (beta-END), and vasopressin (AVP), which are regarded as being involved in the HPA-regulation were investigated in lumbar CSF of 44 suicide attempters.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In suicide attempters, patients with major depressive disorder had significantly lower cerebrospinal fluid DSIP (the body's own peptide) than other patients.

    In plain wordsIn people who had attempted suicide, those with major depression had lower natural DSIP in spinal fluid than the other patients.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseCSF DSIP in major depressive disorder versus other patients
    Study

    n: not reported in source

    Comparator
    Suicide attempters without major depressive disorder
    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    Patients with major depressive disorders had significantly lower SOM, CRH, and DSIP than other patients.
    1 context sentence
    Summary · context
    Corticotropin-releasing hormone (CRH), somatostatin (SOM), delta-sleep-inducing peptide (DSIP), neuropeptide Y (NPY), beta-endorphin (beta-END), and vasopressin (AVP), which are regarded as being involved in the HPA-regulation were investigated in lumbar CSF of 44 suicide attempters.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.