Skip to content

Study · Not a test of the peptide alone · 1992

4 results

Microwave-aided binding of gold-protein-ligand (GPL) complexes. Light microscopic observations in the rat brain.

Cathieni MM, Taban CH

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society1 Mar 1992

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, the peptide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking the peptide.

  1. 01LabNot a test of Delta sleep-inducing peptide (DSIP) aloneEx vivo tissueOther

    Bioassays on isolated organs indicated that the physiological activity of the ligand gold-protein complexes, which included a DSIP complex, was maintained.

    In plain wordsIn lab tests on isolated organs, DSIP attached to gold particles kept its biological activity.

    Outcome
    Not applicablePhysiological activity of the gold-protein-ligand complex
    Study

    n: not reported in source

    isolated organ bioassay
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    Bioassays carried out on isolated organs indicated that the physiological activity of the ligand GPL complex was maintained.
    1 context sentence
    Summary · context
    Instead of using antibodies to bind to specific sites, substance P, delta-sleep-inducing peptide, oxytocin, and dopamine were covalently attached to BSA and then the BSA-ligand complex was adsorbed on 5-nm colloidal gold particles.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  2. 02LabNot a test of Oxytocin aloneEx vivo tissueOther

    Bioassays on isolated organs indicated that the physiological activity of the ligand gold-protein complexes, which included an oxytocin complex, was maintained.

    In plain wordsIn lab tests on isolated organs, oxytocin attached to gold particles kept its biological activity.

    Peptide
    Oxytocin
    Outcome
    Not applicablePhysiological activity of the gold-protein-ligand complex
    Study

    n: not reported in source

    isolated organ bioassay
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    Bioassays carried out on isolated organs indicated that the physiological activity of the ligand GPL complex was maintained.
    1 context sentence
    Summary · context
    Instead of using antibodies to bind to specific sites, substance P, delta-sleep-inducing peptide, oxytocin, and dopamine were covalently attached to BSA and then the BSA-ligand complex was adsorbed on 5-nm colloidal gold particles.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 03LabNot a test of Delta sleep-inducing peptide (DSIP) aloneEx vivo tissueOther

    In rat brain sections, controls with excess unbound ligand showed that labeling with the ligand complexes, which included DSIP, was specific.

    In plain wordsIn rat brain sections, labeling with gold-attached DSIP was specific, as control tests showed.

    Outcome
    Not applicableSpecificity of tissue labeling with the gold-protein-ligand complex
    Study

    ratn: not reported in source

    cryostat sections of unfixed rat brain
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Positive and negative controls performed by addition of BSA-conjugated ligands to the pre-incubation and incubation medium, and displacement of the markers by an excess of unbound ligand in the pre-incubation or the incubation medium, showed the specificity of the tissue labeling.
    1 context sentence
    Summary · context
    Instead of using antibodies to bind to specific sites, substance P, delta-sleep-inducing peptide, oxytocin, and dopamine were covalently attached to BSA and then the BSA-ligand complex was adsorbed on 5-nm colloidal gold particles.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  4. 04LabNot a test of Oxytocin aloneEx vivo tissueOther

    In rat brain sections, controls with excess unbound ligand showed that labeling with the ligand complexes, which included oxytocin, was specific.

    In plain wordsIn rat brain sections, labeling with gold-attached oxytocin was specific, as control tests showed.

    Peptide
    Oxytocin
    Outcome
    Not applicableSpecificity of tissue labeling with the gold-protein-ligand complex
    Study

    ratn: not reported in source

    cryostat sections of unfixed rat brain
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Positive and negative controls performed by addition of BSA-conjugated ligands to the pre-incubation and incubation medium, and displacement of the markers by an excess of unbound ligand in the pre-incubation or the incubation medium, showed the specificity of the tissue labeling.
    1 context sentence
    Summary · context
    Instead of using antibodies to bind to specific sites, substance P, delta-sleep-inducing peptide, oxytocin, and dopamine were covalently attached to BSA and then the BSA-ligand complex was adsorbed on 5-nm colloidal gold particles.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:04 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.