Skip to content

Study · Ex vivo tissue · rat · 1992

2 results

Regional differences in the contractile activity of neuropeptide Y, endothelin, oxytocin and vasopressin: comparison with non-peptidergic constrictors. An in vitro study in the basilar and mesenteric arteries of the rat.

Szabó C, Hardebo JE

Acta physiologica Hungarica1 Jan 1992Cited by 3 (Europe PMC)

PMID1364091 (opens in a new tab)PepBankPUB-01364091
Publisher pageAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueEfficacy outcome

    In isolated rat basilar artery, oxytocin caused contraction, with sensitivity ranked below endothelin and vasopressin and above neuropeptide Y.

    In plain wordsIn lab tests on rat brain arteries, oxytocin made the vessel contract, less strongly than endothelin or vasopressin.

    Peptide
    Oxytocin
    Outcome
    IncreaseContraction of basilar artery
    Study

    ratn: not reported in source

    Comparator
    Endothelin, vasopressin, neuropeptide Y
    Outcome group
    Blood pressure · Cardiovascular
    Studied dose
    10(-11)-10(-7) MAs given in this study (rat).

    Source sentences

    Summary
    BAS was more sensitive in EC50 values to the peptides in the order ENDO > or = VRP > OXY > NPY.
    1 context sentence
    Summary · context
    The vasoconstrictor effect of the peptides neuropeptide Y (NPY), endothelin (ENDO), vasopressin (VPR) and oxytocin (OXY) (10(-11)-10(-7) M) was compared in the isolated basilar (BAS) and mesenteric (MES) arteries of rat.
  2. 02LabEx vivo tissueEfficacy outcome

    In isolated rat mesenteric artery, oxytocin caused no contraction.

    In plain wordsIn lab tests on rat gut arteries, oxytocin did not make the vessel contract.

    Peptide
    Oxytocin
    Outcome
    No significant changeContraction of mesenteric artery
    Study

    ratn: not reported in source

    Outcome group
    Blood pressure · Cardiovascular
    Studied dose
    10(-11)-10(-7) MAs given in this study (rat).

    Source sentences

    Summary
    In MES, OXY and NPY caused no and VPR caused weak contraction, whereas the effect of ENDO was pronounced, with a similar EC50 value as in BAS.
    1 context sentence
    Summary · context
    The vasoconstrictor effect of the peptides neuropeptide Y (NPY), endothelin (ENDO), vasopressin (VPR) and oxytocin (OXY) (10(-11)-10(-7) M) was compared in the isolated basilar (BAS) and mesenteric (MES) arteries of rat.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.