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Study · Ex vivo tissue · frog · 1992

6 results

[The potential-dependent action of the opioid peptide dermorphin].

Babskaia NE

Biulleten' eksperimental'noi biologii i meditsiny1 Nov 1992

PMID1363279 (opens in a new tab)PepBankPUB-01363279
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In frog stomach muscle strips, dermorphin blocked acetylcholine effects.

    In plain wordsIn lab tests, dermorphin blocked acetylcholine effects in frog stomach muscle.

    Peptide
    Dermorphin
    Outcome
    DecreaseAcetylcholine effects
    Study

    frogn: not reported in source

    Stomach muscle strips
    Outcome group
    Receptor activity and mechanism · Gastrointestinal
    Studied dose
    10(-5)-10(-8) MAs given in this study (frog).

    Source sentences

    Summary
    The results show that dermorphin (10(-5)-10(-8) M) blocks acetylcholine effects, spontaneous activity and muscle contractions induced by direct electrical stimulation.
    1 context sentence
    Summary · context
    Dermorphin action was studied on cross-section strip of frog stomach muscle by a mechanographic recorder.
  2. 02LabEx vivo tissueActivity measurement

    In frog stomach muscle strips, dermorphin blocked spontaneous activity.

    In plain wordsIn lab tests, dermorphin blocked spontaneous frog stomach muscle activity.

    Peptide
    Dermorphin
    Outcome
    DecreaseSpontaneous muscle activity
    Study

    frogn: not reported in source

    Stomach muscle strips
    Outcome group
    Receptor activity and mechanism · Gastrointestinal
    Studied dose
    10(-5)-10(-8) MAs given in this study (frog).

    Source sentences

    Summary
    The results show that dermorphin (10(-5)-10(-8) M) blocks acetylcholine effects, spontaneous activity and muscle contractions induced by direct electrical stimulation.
    1 context sentence
    Summary · context
    Dermorphin action was studied on cross-section strip of frog stomach muscle by a mechanographic recorder.
  3. 03LabEx vivo tissueActivity measurement

    In frog stomach muscle strips, dermorphin blocked contractions induced by direct electrical stimulation.

    In plain wordsIn lab tests, dermorphin blocked frog stomach muscle contractions induced by direct electrical stimulation.

    Peptide
    Dermorphin
    Outcome
    DecreaseElectrically induced muscle contractions
    Study

    frogn: not reported in source

    Stomach muscle strips
    Outcome group
    Receptor activity and mechanism · Gastrointestinal
    Studied dose
    10(-5)-10(-8) MAs given in this study (frog).

    Source sentences

    Summary
    The results show that dermorphin (10(-5)-10(-8) M) blocks acetylcholine effects, spontaneous activity and muscle contractions induced by direct electrical stimulation.
    1 context sentence
    Summary · context
    Dermorphin action was studied on cross-section strip of frog stomach muscle by a mechanographic recorder.
  4. 04LabEx vivo tissueMechanism

    In frog stomach muscle strips, dermorphin inhibition of acetylcholine effects, spontaneous activity and electrically induced contractions was hardly reversible.

    In plain wordsIn lab tests, dermorphin's inhibitory effects in frog stomach muscle were hardly reversible.

    Peptide
    Dermorphin
    Outcome
    Not applicableReversibility of inhibition
    Study

    frogn: not reported in source

    Stomach muscle strips
    Outcome group
    Receptor activity and mechanism · Gastrointestinal
    Studied dose
    10(-5)-10(-8) MAs given in this study (frog).

    Source sentences

    Summary
    All the above effects are hardly reversible.
    2 context sentences
    Summary · context
    The results show that dermorphin (10(-5)-10(-8) M) blocks acetylcholine effects, spontaneous activity and muscle contractions induced by direct electrical stimulation.
    Summary · context
    Dermorphin action was studied on cross-section strip of frog stomach muscle by a mechanographic recorder.
  5. 05LabEx vivo tissueActivity measurement

    In frog stomach muscle strips during potassium depolarization, dermorphin failed to block spontaneous activity.

    In plain wordsIn lab tests, dermorphin failed to block spontaneous frog stomach muscle activity during potassium depolarization.

    Peptide
    Dermorphin
    Outcome
    No significant changeSpontaneous activity during potassium depolarization
    Study

    frogn: not reported in source

    Stomach muscle strips
    Outcome group
    Receptor activity and mechanism · Gastrointestinal
    Studied dose
    10(-5)-10(-8) MAs given in this study (frog).

    Source sentences

    Summary
    Dermorphin fails to block spontaneous and evoked activities if it is injected into the incubated medium during K(+)-depolarization (KCI--100 mM) of the muscle.
    1 context sentence
    Summary · context
    Dermorphin action was studied on cross-section strip of frog stomach muscle by a mechanographic recorder.
  6. 06LabEx vivo tissueActivity measurement

    In frog stomach muscle strips during potassium depolarization, dermorphin failed to block evoked activity.

    In plain wordsIn lab tests, dermorphin failed to block evoked frog stomach muscle activity during potassium depolarization.

    Peptide
    Dermorphin
    Outcome
    No significant changeEvoked activity during potassium depolarization
    Study

    frogn: not reported in source

    Stomach muscle strips
    Outcome group
    Receptor activity and mechanism · Gastrointestinal
    Studied dose
    10(-5)-10(-8) MAs given in this study (frog).

    Source sentences

    Summary
    Dermorphin fails to block spontaneous and evoked activities if it is injected into the incubated medium during K(+)-depolarization (KCI--100 mM) of the muscle.
    1 context sentence
    Summary · context
    Dermorphin action was studied on cross-section strip of frog stomach muscle by a mechanographic recorder.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

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