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Study · Animal study (in vivo) · rabbit · 1992

4 results

Quantitative EEG and autonomic patterns of synthetic peptides related to dermorphin.

Marchioni E, Maurelli M, Tartara A

Neuropsychobiology1 Jan 1992Cited by 2 (Europe PMC)

PMID1361972 (opens in a new tab)DOI10.1159/000118900 (opens in a new tab)PepBankPUB-01361972
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In rabbits, dermorphin most effectively increased cortically derived and calculated total power among the tested peptides.

    In plain wordsIn rabbits, dermorphin increased cortical total power most effectively among the tested peptides.

    Peptide
    Dermorphin
    Outcome
    IncreaseCortical total power
    Study

    rabbitn: not reported in source

    Rabbits
    Comparator
    Tested analogues and homologues
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated · intracerebroventricularAs given in this study (rabbit).

    Source sentences

    Summary
    Dermorphin was the most effective in modifying all considered parameters: increase of cortically derived and calculated total power, bradycardia, respiratory depression and hypothermia.
    1 context sentence
    Summary · context
    The effects of dermorphin on EEG and autonomic variables are compared with the effects of 2 analogues and 2 homologues, all administered intracerebroventricularly in the rabbit.
  2. 02AnimalAnimal study (in vivo)Safety outcome

    In rabbits, dermorphin produced the strongest bradycardia among the tested peptides.

    In plain wordsIn rabbits, dermorphin slowed heart rate most strongly among the tested peptides.

    Peptide
    Dermorphin
    Outcome
    DecreaseBradycardia
    Study

    rabbitn: not reported in source

    Rabbits
    Comparator
    Tested analogues and homologues
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated · intracerebroventricularAs given in this study (rabbit).

    Source sentences

    Summary
    Dermorphin was the most effective in modifying all considered parameters: increase of cortically derived and calculated total power, bradycardia, respiratory depression and hypothermia.
    1 context sentence
    Summary · context
    The effects of dermorphin on EEG and autonomic variables are compared with the effects of 2 analogues and 2 homologues, all administered intracerebroventricularly in the rabbit.
  3. 03AnimalAnimal study (in vivo)Safety outcome

    In rabbits, dermorphin produced the strongest respiratory depression among the tested peptides.

    In plain wordsIn rabbits, dermorphin depressed breathing most strongly among the tested peptides.

    Peptide
    Dermorphin
    Outcome
    DecreaseRespiratory depression
    Study

    rabbitn: not reported in source

    Rabbits
    Comparator
    Tested analogues and homologues
    Outcome group
    Adverse events · Respiratory
    Studied dose
    Dose not stated · intracerebroventricularAs given in this study (rabbit).

    Source sentences

    Summary
    Dermorphin was the most effective in modifying all considered parameters: increase of cortically derived and calculated total power, bradycardia, respiratory depression and hypothermia.
    1 context sentence
    Summary · context
    The effects of dermorphin on EEG and autonomic variables are compared with the effects of 2 analogues and 2 homologues, all administered intracerebroventricularly in the rabbit.
  4. 04AnimalAnimal study (in vivo)Safety outcome

    In rabbits, dermorphin produced the strongest hypothermia among the tested peptides.

    In plain wordsIn rabbits, dermorphin lowered body temperature most strongly among the tested peptides.

    Peptide
    Dermorphin
    Outcome
    DecreaseHypothermia
    Study

    rabbitn: not reported in source

    Rabbits
    Comparator
    Tested analogues and homologues
    Outcome group
    Body temperature · Whole body
    Studied dose
    Dose not stated · intracerebroventricularAs given in this study (rabbit).

    Source sentences

    Summary
    Dermorphin was the most effective in modifying all considered parameters: increase of cortically derived and calculated total power, bradycardia, respiratory depression and hypothermia.
    1 context sentence
    Summary · context
    The effects of dermorphin on EEG and autonomic variables are compared with the effects of 2 analogues and 2 homologues, all administered intracerebroventricularly in the rabbit.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

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