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Study · Not a test of the peptide alone · 1992

3 results

High-performance liquid chromatographic assay for the alpha-melanotropin[4,10] fragment analogue (Melanotan-II) in rat plasma.

Ugwu SO, Blanchard J

Journal of chromatography1 Dec 1992Cited by 7 (Europe PMC)

PMID1336500 (opens in a new tab)DOI10.1016/0378-4347(92)80573-9 (opens in a new tab)PepBankPUB-01336500
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Melanotan II.

  1. 01LabNot a test of Melanotan II aloneOther designOther

    The HPLC assay for melanotan II in rat plasma gave linear calibration curves from 100 to 1000 ng/ml.

    In plain wordsIn lab tests, the melanotan II assay in rat plasma was linear from 100 to 1000 nanograms per millilitre.

    Peptide
    Melanotan II
    Outcome
    Not applicableHPLC calibration range
    Study

    ratn: not reported in source

    Rat plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Linear range
    100 to 1000 ng/ml
    rat plasma

    Source sentences

    Summary
    Calibration curves were linear over the range 100-1000 ng/ml for rat plasma.
    1 context sentence
    Summary · context
    A high-performance liquid chromatographic (HPLC) procedure has been developed for the quantification of Melanotan-II (MT-II), a cyclic heptapeptide which promotes rapid tanning of the skin, in rat plasma.

    In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.

  2. 02LabNot a test of Melanotan II aloneOther designOther

    The HPLC assay for melanotan II in rat plasma had a detection limit of 50 ng/ml.

    In plain wordsIn lab tests, the melanotan II assay in rat plasma could detect as little as 50 nanograms per millilitre.

    Peptide
    Melanotan II
    Outcome
    Not applicableHPLC detection limit
    Study

    ratn: not reported in source

    Rat plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Detection limit
    50 ng/ml
    rat plasma

    Source sentences

    Summary
    The method is reproducible and reliable with a detection limit of 50 ng/ml in plasma.
    1 context sentence
    Summary · context
    A high-performance liquid chromatographic (HPLC) procedure has been developed for the quantification of Melanotan-II (MT-II), a cyclic heptapeptide which promotes rapid tanning of the skin, in rat plasma.

    In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.

  3. 03LabNot a test of Melanotan II aloneOther designOther

    Within-day and between-day precision and accuracy of the HPLC assay for melanotan II in rat plasma were below 7%.

    In plain wordsIn lab tests, the melanotan II assay in rat plasma had precision and accuracy errors below 7 percent.

    Peptide
    Melanotan II
    Outcome
    Not applicableHPLC precision and accuracy
    Study

    ratn: not reported in source

    Rat plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Coefficient of variation and relative error
    < 7%
    rat plasma

    Source sentences

    Summary
    Within- and between-day precision and accuracy reported as coefficient of variation and relative error, respectively, were < 7%.
    1 context sentence
    Summary · context
    A high-performance liquid chromatographic (HPLC) procedure has been developed for the quantification of Melanotan-II (MT-II), a cyclic heptapeptide which promotes rapid tanning of the skin, in rat plasma.

    In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 10:21 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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