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Study · Animal study (in vivo) · rat · 1992

3 results

[The frequency composition of the brain electrical activity in rats after the use of the delta-sleep peptide and its analogs].

Vorob'ev VV, Shibaev NV, Prudchenko IA, Mikhaleva II

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova1 Sept 1992

PMID1336284 (opens in a new tab)PepBankPUB-01336284
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In freely moving rats, DSIP first suppressed fast (20-26 Hz) oscillations (up to 20 min after injection) and then augmented them in later intervals.

    In plain wordsIn rats, DSIP first reduced and then increased fast brain-wave activity after injection.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    MixedFast (20-26 Hz) electrocorticogram oscillations
    Study

    ratn = 18

    Outcome group
    Brain and neuronal activity · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In autumn series of experiments carried out on 18 animals was revealed the phase action of DSIP being manifested in initial (up to 20 min after the injection) suppression of fast (20-26 Hz) oscillations in electrocorticograms and their augmentation in subsequent intervals.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intraperitoneal DSIP significantly increased delta-waves in the electrical activity of the Putamen.

    In plain wordsIn rats, DSIP injected into the abdomen increased slow delta brain waves in a deep brain region.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseDelta-waves in Putamen electrical activity
    Study

    ratn = 6

    Outcome group
    Brain and neuronal activity · Nervous system and cognition
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    In spring-summer series of experiments carried out in 6 animals was revealed a significant increase of the delta-waves in electrical activity of the Putamen after intraperitoneal injection of DSIP and its first analogue.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intraventricular DSIP induced stable augmentation of 14-16 Hz oscillations in the neocortex.

    In plain wordsIn rats, DSIP injected into the brain ventricles increased brain-wave activity at 14-16 Hz in the neocortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Increase14-16 Hz neocortex oscillations
    Study

    ratn: not reported in source

    Outcome group
    Brain and neuronal activity · Nervous system and cognition
    Studied dose
    Dose not stated · intraventricularAs given in this study (rat).

    Source sentences

    Summary
    Under the conditions of intraventricular injection DSIP induced stable augmentation of oscillations in a diapason of 14-16 Hz in the neocortex, and its analogues induced similar changes in a nearby frequency diapason of 9.6-11 Hz.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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