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Study · Measured the body's own peptide · 1992

2 results

Survey of neuropeptide gene expression in tumor cell lines.

Verbeeck MA, Mummery CL, Feijen A, Burbach JP

Pathobiology : journal of immunopathology, molecular and cellular biology1 Jan 1992Cited by 8 (Europe PMC)

PMID1320892 (opens in a new tab)DOI10.1159/000163711 (opens in a new tab)PepBankPUB-01320892
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In 36 tumor cell lines, only very low oxytocin mRNA signals were detected, in the rat pituitary tumor line GH4C2 and the rat pancreas tumor line RIN5.

    In plain wordsIn cultured tumor cells, only two rat cell lines showed very low signals for the body's own oxytocin gene.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin mRNA in tumor cell lines
    Study

    ratn = 36

    tumor cell lines
    Outcome group
    Endogenous peptide levels · Cancer

    Source sentences

    Summary
    Very low oxytocin (OT) mRNA hybridization signals were detected in the rat pituitary tumor cell line GH4C2 and the rat pancreas tumor cell line RIN5.
    1 context sentence
    Summary · context
    The presence of 3 different neuropeptide mRNAs with a strict cell-specific expression in vivo was investigated in 13 tumor cell lines from neuroendocrine and in 23 tumor cell lines from non-neuroendocrine origin.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Mechanism

    In tumor cell lines, treatments that induce differentiation did not change the low incidence of oxytocin gene expression.

    In plain wordsIn cultured tumor cells, treatments that push cells to mature did not change the rare activity of the body's own oxytocin gene.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin mRNA after differentiation-inducing treatments
    Study

    ratn: not reported in source

    tumor cell lines
    Outcome group
    Endogenous peptide levels · Cancer

    Source sentences

    Summary
    The low incidence of VP, OT and POMC gene expression in the tested tumor cell lines was not influenced by treatments inducing differentiation.
    1 context sentence
    Summary · context
    The presence of 3 different neuropeptide mRNAs with a strict cell-specific expression in vivo was investigated in 13 tumor cell lines from neuroendocrine and in 23 tumor cell lines from non-neuroendocrine origin.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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