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Study · Not a test of the peptide alone · 1976

4 results

Effects of oxamate, an inhibitor of lactate dahydrogenase, upon the spontaneous or oxytocin-induced motility and over pyruvate levels of uterine horns isolated from ovariectomized or estrus rats.

Gimeno AL, Goldraij A, Gimeno MF, Santillan de Torres R

Reproduccion1 Jan 1976Cited by 2 (Europe PMC)

PMID1036172 (opens in a new tab)PepBankPUB-01036172
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01LabNot a test of Oxytocin aloneEx vivo tissueOther

    In uterine horns from induced estrus rats, oxamate at 10 mM did not affect oxytocin-triggered functional activity.

    In plain wordsIn lab tests of uterine tissue from induced estrus rats, 10 mM oxamate did not affect oxytocin-triggered activity.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin-triggered uterine functional activity in induced estrus rats after oxamate
    Study

    ratn: not reported in source

    isolated uterine horns
    Comparator
    without oxamate
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    The stability with time of the spontaneous as well as the oxytocin-triggered functional activity of uterine borns isolated from induced estrus rats and immersed in a medium with lactate as the substrate was not affected by the presence of oxomate (an inhibitor of lactate dehydrogenase) at 10 or 20mM.
    1 context sentence
    Title · context
    Effects of oxamate, an inhibitor of lactate dahydrogenase, upon the spontaneous or oxytocin-induced motility and over pyruvate levels of uterine horns isolated from ovariectomized or estrus rats.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02LabNot a test of Oxytocin aloneEx vivo tissueOther

    In uterine horns from rats castrated for 15 days, oxamate significantly reduced oxytocin-driven motility.

    In plain wordsIn lab tests of uterine tissue from rats castrated for 15 days, oxamate reduced oxytocin-driven motility.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin-driven uterine motility in castrated rats after oxamate
    Study

    ratn: not reported in source

    isolated uterine horns
    Comparator
    without oxamate
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    On the contrary, the oxytocin-driven and the spontaneous motility of preparations obtained from 15 days castrated rats diminished significantly following in addition of the enzyme inhibitor.
    1 context sentence
    Title · context
    Effects of oxamate, an inhibitor of lactate dahydrogenase, upon the spontaneous or oxytocin-induced motility and over pyruvate levels of uterine horns isolated from ovariectomized or estrus rats.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 03LabNot a test of Oxytocin aloneEx vivo tissueOther

    In uterine horns from induced estrus rats, oxamate at 20 mM did not affect oxytocin-triggered functional activity.

    In plain wordsIn lab tests of uterine tissue from induced estrus rats, 20 mM oxamate did not affect oxytocin-triggered activity.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin-triggered uterine functional activity in induced estrus rats after 20 mM oxamate
    Study

    ratn: not reported in source

    isolated uterine horns
    Comparator
    without oxamate
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    The stability with time of the spontaneous as well as the oxytocin-triggered functional activity of uterine borns isolated from induced estrus rats and immersed in a medium with lactate as the substrate was not affected by the presence of oxomate (an inhibitor of lactate dehydrogenase) at 10 or 20mM.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  4. 04LabNot a test of Oxytocin aloneEx vivo tissueOther

    In uterine horns from ovariectomized rats injected with 17-beta estradiol, functional sensitivity toward oxamate was absent again.

    In plain wordsIn lab tests of uterine tissue from estradiol-treated ovariectomized rats, functional sensitivity toward oxamate was absent again.

    Peptide
    Oxytocin
    Outcome
    No significant changeFunctional sensitivity toward oxamate in estradiol-treated ovariectomized rat uterine horns
    Study

    ratn: not reported in source

    isolated uterine horns
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    Furthermore, uterine borns from ovariectomized animals injected with 17-beta estradiol, regain the lack of functional sensivity towards oxamate.
    2 context sentences
    Summary · context
    On the contrary, the oxytocin-driven and the spontaneous motility of preparations obtained from 15 days castrated rats diminished significantly following in addition of the enzyme inhibitor.
    Summary · context
    The stability with time of the spontaneous as well as the oxytocin-triggered functional activity of uterine borns isolated from induced estrus rats and immersed in a medium with lactate as the substrate was not affected by the presence of oxomate (an inhibitor of lactate dehydrogenase) at 10 or 20mM.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 11:11 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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