A new approach to the hormonal treatment of impotentia erectionis.

Lidberg L, Sternthal V

Pharmakopsychiatrie, Neuro-Psychopharmakologie1 Jan 1977Cited by 5 (Europe PMC)

PMID887645DOI10.1055/s-0028-1094514PepBankPUB-00887645

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. 6 results from people.

01HumanOther designEfficacy outcome
In out-patients with impotentia erectionis, oral oxytocin 600 IU daily produced no significant therapeutic effect.
In plain wordsIn out-patients with erection problems, oral oxytocin 600 IU daily had no significant therapeutic effect.
Peptide
Oxytocin
Outcome
No significant changeTherapeutic effect at 600 IU daily
Study
n = 10
Outcome group
Sexual function · Reproductive and sexual health
Studied dose
600 IU daily · oral · minimum of 7 weeksAs given in this study (human).
Source sentences
Summary
The daily oral dose of 600 IU produced no significant therapeutic effect.
3 context sentences(design, population, supporting numbers)
Summary · context
The influence of oraly administered synthetic oxytocin (Syntocinon, Sandoz) on the impotentia erectionis has been studied in a double-blind trial in comparison to placebo.
Summary · context
Twenty-nine out-patients divided into 3 groups were treated for a minimum of 7 weeks.
Summary · context
Nine patients were given 300 IU daily, ten patients 600 IU daily and further 10 patients placebo.
Report a problemFND-0088764504
02HumanOther designEfficacy outcome
In out-patients with impotentia erectionis, oral oxytocin 300 IU daily showed the best therapeutic results.
In plain wordsIn out-patients with erection problems, oral oxytocin 300 IU daily had the best therapeutic results.
Peptide
Oxytocin
Outcome
IncreaseOverall therapeutic results at 300 IU daily
Study
n = 9
Outcome group
Sexual function · Reproductive and sexual health
Studied dose
300 IU daily · oral · minimum of 7 weeksAs given in this study (human).
Source sentences
Summary
The treatment with 300 IU of oxytocin daily has shown the best therapeutic results.
3 context sentences(design, population, supporting numbers)
Summary · context
The influence of oraly administered synthetic oxytocin (Syntocinon, Sandoz) on the impotentia erectionis has been studied in a double-blind trial in comparison to placebo.
Summary · context
Twenty-nine out-patients divided into 3 groups were treated for a minimum of 7 weeks.
Summary · context
Nine patients were given 300 IU daily, ten patients 600 IU daily and further 10 patients placebo.
Report a problemFND-0088764501
03HumanOther designEfficacy outcome
In out-patients with impotentia erectionis, oxytocin 300 IU daily improved sexual interest more than placebo (P less than 0.05).
In plain wordsIn out-patients with erection problems, 300 IU daily oral oxytocin improved sexual interest more than placebo (P less than 0.05).
Peptide
Oxytocin
Outcome
IncreaseSexual interest at 300 IU daily
Study
n: not reported in source
Comparator
placebo
Outcome group
Sexual function · Reproductive and sexual health
Studied dose
300 IU daily · oral · minimum of 7 weeksAs given in this study (human).
Source sentences
Summary
The difference between this group and the placebo group was statistically significant regarding the overall parameters sexual interest and sexual capability (P less than 0.05) and P less than 0.10 respectively).
3 context sentences(design, population, supporting numbers)
Summary · context
The influence of oraly administered synthetic oxytocin (Syntocinon, Sandoz) on the impotentia erectionis has been studied in a double-blind trial in comparison to placebo.
Summary · context
Twenty-nine out-patients divided into 3 groups were treated for a minimum of 7 weeks.
Summary · context
Nine patients were given 300 IU daily, ten patients 600 IU daily and further 10 patients placebo.
Report a problemFND-0088764502
04HumanOther designEfficacy outcome
In out-patients with impotentia erectionis, oxytocin 300 IU daily improved sexual capability more than placebo (P less than 0.10).
In plain wordsIn out-patients with erection problems, 300 IU daily oral oxytocin improved sexual capability more than placebo (P less than 0.10).
Peptide
Oxytocin
Outcome
IncreaseSexual capability at 300 IU daily
Study
n: not reported in source
Comparator
placebo
Outcome group
Sexual function · Reproductive and sexual health
Studied dose
300 IU daily · oral · minimum of 7 weeksAs given in this study (human).
Source sentences
Summary
The difference between this group and the placebo group was statistically significant regarding the overall parameters sexual interest and sexual capability (P less than 0.05) and P less than 0.10 respectively).
3 context sentences(design, population, supporting numbers)
Summary · context
The influence of oraly administered synthetic oxytocin (Syntocinon, Sandoz) on the impotentia erectionis has been studied in a double-blind trial in comparison to placebo.
Summary · context
Twenty-nine out-patients divided into 3 groups were treated for a minimum of 7 weeks.
Summary · context
Nine patients were given 300 IU daily, ten patients 600 IU daily and further 10 patients placebo.
Report a problemFND-0088764503
05HumanOther designSafety outcome
In out-patients with impotentia erectionis, oxytocin at both oral doses was well tolerated.
In plain wordsIn out-patients with erection problems, both oral oxytocin doses were well tolerated.
Peptide
Oxytocin
Outcome
Not applicableTolerability at either oral dose
Study
n: not reported in source
Outcome group
Adverse events · Whole body
Studied dose
300 or 600 IU daily · oral · minimum of 7 weeksAs given in this study (human).
Source sentences
Summary
Oxytocin in both dosage schedules was well tolerated and no untoward side effects were observed.
3 context sentences(design, population, supporting numbers)
Summary · context
The influence of oraly administered synthetic oxytocin (Syntocinon, Sandoz) on the impotentia erectionis has been studied in a double-blind trial in comparison to placebo.
Summary · context
Twenty-nine out-patients divided into 3 groups were treated for a minimum of 7 weeks.
Summary · context
Nine patients were given 300 IU daily, ten patients 600 IU daily and further 10 patients placebo.
Report a problemFND-0088764505
06HumanOther designSafety outcome
In out-patients with impotentia erectionis, no untoward side effects were observed with oxytocin at either oral dose.
In plain wordsIn out-patients with erection problems, no untoward side effects were observed with either oral oxytocin dose.
Peptide
Oxytocin
Outcome
Not applicableUntoward side effects at either oral dose
Study
n: not reported in source
Outcome group
Adverse events · Whole body
Studied dose
300 or 600 IU daily · oral · minimum of 7 weeksAs given in this study (human).
Source sentences
Summary
Oxytocin in both dosage schedules was well tolerated and no untoward side effects were observed.
1 context sentence(design, population, supporting numbers)
Summary · context
The influence of oraly administered synthetic oxytocin (Syntocinon, Sandoz) on the impotentia erectionis has been studied in a double-blind trial in comparison to placebo. Twenty-nine out-patients divided into 3 groups were treated for a minimum of 7 weeks. Nine patients were given 300 IU daily, ten…
Report a problemFND-0088764506

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
12 Oct 2026, 11:11 UTC
Study results updated
Version 1
9 Oct 2026, 02:51 UTC
First added · source update from Europe PMC

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