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Study · Animal study (in vivo) · rat · 1977

2 results

Modulation of heroin self-administration by neurohypophyseal principles.

Van Ree JM, De Wied D

European journal of pharmacology1 May 1977Cited by 52 (Europe PMC)

PMID872873 (opens in a new tab)DOI10.1016/0014-2999(77)90132-7 (opens in a new tab)PepBankPUB-00872873
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, PLG facilitated intravenous heroin self-administration.

    In plain wordsIn rats, PLG increased intravenous heroin self-administration.

    Peptide
    MIF-1 (Pro-Leu-Gly-NH2)
    Outcome
    IncreaseHeroin self-administration
    Study

    ratn: not reported in source

    intravenous heroin self-administration
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Desglycinamide9, arginine8-vasopressin and pressinamide reduced, while oxytocin and its C-terminal tripeptide, prolyl-leucyl-glycinamide facilitated this behavior.
    1 context sentence
    Summary · context
    Neuropeptides related to hypothalomic-neurohypophyseal hormones affect intravenous heroin self-administration behavior in rats.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, oxytocin facilitated intravenous heroin self-administration.

    In plain wordsIn rats, oxytocin increased intravenous heroin self-administration.

    Peptide
    Oxytocin
    Outcome
    IncreaseHeroin self-administration
    Study

    ratn: not reported in source

    intravenous heroin self-administration
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Desglycinamide9, arginine8-vasopressin and pressinamide reduced, while oxytocin and its C-terminal tripeptide, prolyl-leucyl-glycinamide facilitated this behavior.
    1 context sentence
    Summary · context
    Neuropeptides related to hypothalomic-neurohypophyseal hormones affect intravenous heroin self-administration behavior in rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 18:59 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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