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Study · Animal study (in vivo) · mouse · 1979

3 results

Regulation of contact sensitivity to DNFB in the mouse: effects of adult thymectomy and thymic factor.

Erard D, Charreire J, Auffredou MT, Galanaud P, Bach JF

Journal of immunology (Baltimore, Md. : 1950)1 Oct 1979Cited by 9 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice, FTS restored DNFB contact sensitivity when injected 3 to 9 weeks after adult thymectomy.

    In plain wordsIn mice, FTS restored DNFB contact sensitivity when injected 3 to 9 weeks after thymus removal.

    Outcome
    IncreaseDNFB contact sensitivity early after thymectomy
    Study

    mousen: not reported in source

    adult thymectomized mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · injectionAs given in this study (mouse).

    Source sentences

    Summary
    A circulating thymic factor (FTS) is able to restore the contact sensitivity response to DNFB when injected 3 to 9 weeks after ATX but not 16 weeks later.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In mice, FTS did not restore DNFB contact sensitivity when injected 16 weeks after adult thymectomy.

    In plain wordsIn mice, FTS did not restore DNFB contact sensitivity when injected 16 weeks after thymus removal.

    Outcome
    No significant changeDNFB contact sensitivity late after thymectomy
    Study

    mousen: not reported in source

    adult thymectomized mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · injectionAs given in this study (mouse).

    Source sentences

    Summary
    A circulating thymic factor (FTS) is able to restore the contact sensitivity response to DNFB when injected 3 to 9 weeks after ATX but not 16 weeks later.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In normal mice, FTS depressed DNFB contact sensitivity through a cyclophosphamide-sensitive T-cell subset.

    In plain wordsIn normal mice, FTS reduced DNFB contact sensitivity through a cyclophosphamide-sensitive T-cell subset.

    Outcome
    DecreaseDNFB contact sensitivity in normal mice
    Study

    mousen: not reported in source

    normal mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · injectionAs given in this study (mouse).

    Source sentences

    Summary
    By contrast, FTS has a depressive effect on the contact sensitivity response to DNFB of normal mice through a cyclophosphamide-sensitive T cell subset.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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