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Study · Measured the body's own peptide · 1979

4 results

Radioimmunologic localization of vasoactive intestinal polypeptide in hypothalamic and extrahypothalamic sites in the rat brain.

Samson WK, Said SI, McCann SM

Neuroscience letters1 May 1979Cited by 48 (Europe PMC)

PMID460720 (opens in a new tab)DOI10.1016/0304-3940(79)96073-7 (opens in a new tab)PepBankPUB-00460720
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rat brain, the highest concentrations of VIP were found in the cerebral cortex, suprachiasmatic nucleus and medial amygdaloid nucleus.

    In plain wordsIn rats, the body's own VIP was highest in the cerebral cortex and two deeper brain areas.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableHighest VIP concentrations in rat brain
    Study

    ratn: not reported in source

    rat brain regions, radioimmunoassay
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Highest concentrations of VIP were found in cerebral cortex, suprachiasmatic nucleus, and medial amygdaloid nucleus.
    1 context sentence
    Summary · context
    Using a specific radioimmunoassay (RIA), we have quantitated the hypothalamic and extrahypothalamic distribution of vasoactive intestinal polypeptide (VIP) in the rat brain.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rat brain, lower VIP concentrations were found in the anterior hypothalamic area, medial preoptic area, peri- and paraventricular nuclei, and hippocampus.

    In plain wordsIn rats, the body's own VIP was lower in several hypothalamic areas and the hippocampus.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableLower VIP concentrations in hypothalamic and hippocampal regions
    Study

    ratn: not reported in source

    rat brain regions, radioimmunoassay
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Lower concentrations were found in the anterior hypothalamic area, medial preoptic area, peri- and paraventricular nuclei, and hippocampus.
    1 context sentence
    Summary · context
    Using a specific radioimmunoassay (RIA), we have quantitated the hypothalamic and extrahypothalamic distribution of vasoactive intestinal polypeptide (VIP) in the rat brain.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, significant levels of VIP were found in the anterior pituitary.

    In plain wordsIn rats, the body's own VIP was present in significant amounts in the anterior pituitary.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP in anterior pituitary
    Study

    ratn: not reported in source

    rat brain regions, radioimmunoassay
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Significant levels of VIP were also found in the anterior pituitary.
    1 context sentence
    Summary · context
    Using a specific radioimmunoassay (RIA), we have quantitated the hypothalamic and extrahypothalamic distribution of vasoactive intestinal polypeptide (VIP) in the rat brain.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In rat brain, very little VIP was detected in the median eminence and the cerebellar cortex.

    In plain wordsIn rats, the body's own VIP was very low in the median eminence and the cerebellar cortex.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP in median eminence and cerebellar cortex
    Study

    ratn: not reported in source

    rat brain regions, radioimmunoassay
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Very little VIP was detected in median eminence and cerebellar cortex.
    1 context sentence
    Summary · context
    Using a specific radioimmunoassay (RIA), we have quantitated the hypothalamic and extrahypothalamic distribution of vasoactive intestinal polypeptide (VIP) in the rat brain.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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