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Study · Animal study (in vivo) · mouse · 1979

2 results

Neonatal thymus grafts. I. Studies on the regulation of the level of circulating thymic factor (FTS).

Tubiana N, Dardenne M

Immunology1 Feb 1979Cited by 4 (Europe PMC)

PMID437830 (opens in a new tab)PepBankPUB-00437830
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In mice after synthetic FTS injections, circulating FTS initially increased and then returned near the previous range.

    In plain wordsIn mice after synthetic FTS injections, circulating FTS first increased, then returned near its previous range.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    MixedFTS levels after synthetic FTS injection
    Study

    mousen: not reported in source

    normal and thymectomized mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · injectionAs given in this study (mouse).

    Source sentences

    Summary
    In all cases, after an initial increase over the normal value, FTS levels returned close to the previous range, indicating the existence of some homeostatic mechanism of FTS secretion.
    1 context sentence
    Summary · context
    An approach of this regulation has been attempted by disrupting the FTS level either by neonatal thymus grafting in adult normal and thymectomized animals, or by injections of synthetic thymic factor into normal, thymectomized mice, grafted or ungrafted.

Studies that did not test the peptide alone1

In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymulin (serum thymic factor).

  1. 02AnimalNot a test of Thymulin (serum thymic factor) aloneAnimal study (in vivo)Mechanism

    In mice after neonatal thymus grafting, circulating FTS initially increased and then returned near the previous range.

    In plain wordsIn mice after thymus grafting, natural FTS levels first increased, then returned near their previous range.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    MixedFTS levels after thymus grafting
    Study

    mousen: not reported in source

    normal and thymectomized mice
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    In all cases, after an initial increase over the normal value, FTS levels returned close to the previous range, indicating the existence of some homeostatic mechanism of FTS secretion.
    1 context sentence
    Summary · context
    An approach of this regulation has been attempted by disrupting the FTS level either by neonatal thymus grafting in adult normal and thymectomized animals, or by injections of synthetic thymic factor into normal, thymectomized mice, grafted or ungrafted.

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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