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Study · Measured the body's own peptide · 1978

4 results

Radioimmunoassay of DSIP-like material in rat brain.

Kastin AJ, Nissen C, Schally AV, Coy DH

Brain research bulletin1 Nov 1978Cited by 43 (Europe PMC)

PMID318193 (opens in a new tab)DOI10.1016/0361-9230(78)90019-9 (opens in a new tab)PepBankPUB-00318193
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, the radioimmunoassay detected the body's own DSIP-like immunoreactivity in the brain.

    In plain wordsIn rats, the body's own DSIP-like material was detected in the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-like immunoreactivity in rat brain
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    With this assay, DSIP-like immunoreactivity was detected in the brain of rats.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, the highest brain values of the body's own DSIP-like immunoreactivity were found in the thalamus.

    In plain wordsIn rats, natural DSIP-like material was highest in the thalamus, a part of the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableRegional DSIP-like immunoreactivity (thalamus)
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Measurements

    DSIP-like immunoreactivity
    11.9 pg/mg
    rat thalamus

    Source sentences

    Summary
    The highest brain values were found in the thalamus (11.9 +/- 1.3 pg/mg).

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone2

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 03LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    Antibodies raised against synthetic DSIP in a rabbit showed no cross-reactivity with 19 naturally occurring peptides or analogues and were used to set up a radioimmunoassay.

    In plain wordsIn lab tests, an antibody made against DSIP did not react with 19 other peptides and was used to build a DSIP assay.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeAntibody cross-reactivity with 19 other peptides
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    Antibodies generated in a rabbit by immunization with synthetic delta-sleep inducing peptide (DSIP) showed no cross-reactivity with 19 naturally-occurring peptides or analogues and were used to establish a radioimmunoassay.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  2. 04LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cell-free)Other

    In the radioimmunoassay, the dose-response curve of the tracer N-Tyr-DSIP was exactly parallel to that of DSIP.

    In plain wordsIn lab tests, the labeled DSIP tracer responded in the assay in the same way as DSIP itself.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeTracer N-Tyr-DSIP dose-response curve versus DSIP
    Study

    n: not reported in source

    Comparator
    DSIP
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    the dose-response curve for N-Tyr-DSIP was exactly parallel to that for DSIP.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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