Anti-thymosin fraction 5 and 6 antisera, but not anti-thymosin alpha‑1 antiserum, inhibited the stimulatory effect of human thymus epithelial conditioned medium on mouse thymocytes.
In plain wordsIn lab tests, an antiserum against thymosin alpha‑1 did not block the effect of thymus cell medium on mouse thymocytes, unlike two other antisera.
- Peptide
- Thymosin alpha-1
- Outcome
- No significant changeBlock of HTECM stimulation of Con A and PHA responses by anti-thymosin alpha 1 antiserum
- Study
mousen: not reported in source
Mouse thymocytes with human thymus epithelial culture conditioned medium- Comparator
- Anti-thymosin fraction 5 and 6 antisera
- Outcome group
- Immune response · Immune and inflammation
Source sentences
Anti-thymosin fraction 5 and 6, but not anti-thymosin-alpha 1, were found to inhibit the stimulatory effect of HTECM on both Con A and PHA responses.
1 context sentence(design, population, supporting numbers)
Therefore we tested the ability of rabbit antisera to different thymosin fractions (thymosin fractions 5, 6 and alpha 1) of both bovine and human origin to block the stimulatory effect of HTECM on Con A and PHA response of mouse thymocytes.
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.