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Study · Ex vivo tissue · 1977

2 results

E-rosette forming lymphocytes in acute leukemia before and after cell incubation with human serum thymic factor.

Ozger Topuz U, Okçuoglu Cavdar A, Astaldi G

Bollettino dell'Istituto sieroterapico milanese1 Nov 1977

PMID304352 (opens in a new tab)PepBankPUB-00304352
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In leukocytes from acute lymphoblastic leukemia patients, serum thymic factor increased E-positive cells in four of twenty-four patients.

    In plain wordsIn lab tests with leukemia samples, serum thymic factor increased E-positive cells in four of twenty-four samples.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseE-rosette-positive cells
    Study

    humann = 24

    Peripheral blood leukocytes from patients with acute lymphoblastic leukemia
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In four out of twenty-four patients tested, the thymic factor incubation of peripheral blood mononuclears increased the number of E+ cells.
    1 context sentence
    Summary · context
    The Authors studied the effect of the human serum thymic factor on the peripheral blood leukocytes from ALL patients, by testing the frequency of the E+ cells by means of the E rosette assay before and after cell incubation with this factor.
  2. 02LabEx vivo tissueMechanism

    In leukocytes from acute lymphoblastic leukemia patients, serum thymic factor induced E-negative to E-positive conversion among null cells.

    In plain wordsIn lab tests with leukemia samples, serum thymic factor changed E-negative null cells into E-positive cells.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    Not applicableE-negative to E-positive cell conversion
    Study

    humann: not reported in source

    Peripheral blood leukocytes from patients with acute lymphoblastic leukemia
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The shift from E- to E+ cells caused by the human serum thymic factor occurred among null cells (E-, SM-Ig-).
    1 context sentence
    Summary · context
    The Authors studied the effect of the human serum thymic factor on the peripheral blood leukocytes from ALL patients, by testing the frequency of the E+ cells by means of the E rosette assay before and after cell incubation with this factor.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

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