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Study · Animal study (in vivo) · rabbit · 1977

2 results

Characterization of a delta-electroencephalogram (-sleep)-inducing peptide.

Schoenenberger GA, Monnier M

Proceedings of the National Academy of Sciences of the United States of America1 Mar 1977Cited by 39 (Europe PMC)

PMID265572 (opens in a new tab)PMCIDPMC430668 (opens in a new tab)DOI10.1073/pnas.74.3.1282 (opens in a new tab)PepBankPUB-00265572
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, intraventricular synthetic DSIP, unlike its metabolites and analogues, significantly and specifically enhanced delta EEG patterns.

    In plain wordsIn rabbits, DSIP infused into the brain ventricles increased slow-wave brain activity, which its related peptides did not do.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseDelta EEG pattern
    Study

    rabbitn = 58

    Outcome group
    Sleep · Sleep
    Studied dose
    Dose not stated · intraventricularAs given in this study (rabbit).

    Source sentences

    Summary
    Only the delta-sleep-inducing peptide (snythetic) showed significant and specific enhancement/induction of delta and spindle electroencephalogram patterns.
    2 context sentences
    Summary · context
    All nine synthetic peptides were infused intraventricularly in rabbits under double-blind conditions.
    Summary · context
    A total of 58 rabbits including controls were evaluated.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, intraventricular synthetic DSIP, unlike its metabolites and analogues, significantly and specifically enhanced spindle EEG patterns.

    In plain wordsIn rabbits, DSIP infused into the brain ventricles increased sleep-spindle brain activity, which its related peptides did not do.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseSpindle EEG pattern
    Study

    rabbitn = 58

    Outcome group
    Sleep · Sleep
    Studied dose
    Dose not stated · intraventricularAs given in this study (rabbit).

    Source sentences

    Summary
    Only the delta-sleep-inducing peptide (snythetic) showed significant and specific enhancement/induction of delta and spindle electroencephalogram patterns.
    2 context sentences
    Summary · context
    All nine synthetic peptides were infused intraventricularly in rabbits under double-blind conditions.
    Summary · context
    A total of 58 rabbits including controls were evaluated.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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