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Study · Non-randomized trial · n = 17 · 1975

1 result

The plasmatic 11-hydroxy-corticosteroid response in the human to a synthetic octadecapeptide corticotrophin (C-41795-Ba).

Duran F, Torres J, Charro A, Bosch AO

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme1 Nov 1975Cited by 2 (Europe PMC)

PMID174989 (opens in a new tab)DOI10.1055/s-0028-1093712 (opens in a new tab)PepBankPUB-00174989
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanNon-randomized trialActivity measurement

    In normal young males, tetracosactrin had lower adrenal-response potency than C-41795-Ba.

    In plain wordsIn normal young males, tetracosactrin had lower potency than C-41795-Ba in stimulating adrenal responses.

    Peptide
    Cosyntropin
    Outcome
    DecreaseAdrenal response potency
    Study

    n = 17

    Comparator
    C-41795-Ba
    Outcome group
    Adrenal Function · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    C-41795-Ba polypeptide shows a higher potency than tetracosactrin.
    1 context sentence
    Summary · context
    The adrenal response as measured by the plasmatic changes in 11-hydroxy-corticosteroid (11-OHCS) concentration following the administration of a synthetic octadecapeptide (C-41795-Ba) was compared in 17 normal young males with that obtained with the commercially available tetracosactrin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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