In severe acute asthma without prior corticosteroid treatment, tetracosactrin depot was linked to satisfactory improvement at a rate comparable to intravenous hydrocortisone hemisuccinate.
In plain wordsIn severe acute asthma without prior steroid treatment, tetracosactrin was linked to improvement comparable to intravenous hydrocortisone.
- Peptide
- Cosyntropin
- Outcome
- Direction not reportedClinical improvement in severe acute asthma
- Study
n: not reported in source
- Comparator
- Intravenous hydrocortisone hemisuccinate
- Outcome group
- Respiratory function · Respiratory
- Studied dose
- Dose not stated · injectionAs given in this study (human).
Source sentences
Patients who had not previously received treatment with corticosteroids responded satisfactorily to repeated daily injections of tetracosactrin depot, the rate of improvement being comparable to that observed in other patients treated with intravenous hydrocortisone hemisuccinate.
1 context sentence(design, population, supporting numbers)
A study of 23 patients admitted to hospital with severe acute asthma is reported in which plasma cortisol level on admission was significantly correlated with the degree of acidaemia and pulse rate.