Skip to content

Study · Animal study (in vivo) · rat · 1976

5 results

Influence of cerebrolysin(r) on the resistance of rats to anoxia.

Trojanová M, Karásek F, Pruzková V, Mourek J

Physiologia Bohemoslovaca1 Jan 1976Cited by 1 (Europe PMC)

PMID135987 (opens in a new tab)PepBankPUB-00135987
Publisher pageAsk about this study
Jump to 5 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, single cerebrolysin injections did not affect resistance to anoxia, regardless of age.

    In plain wordsIn rats, a single cerebrolysin injection did not change resistance to oxygen deprivation at any age.

    Peptide
    Cerebrolysin
    Outcome
    No significant changeAnoxia resistance after single injection
    Study

    ratn: not reported in source

    Rats exposed to anoxia
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Single injections of Cerebrolysin(R) did not affect the resistance of rats to anoxia, irrespective of age.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, ten maternal cerebrolysin injections during pregnancy significantly increased offspring resistance to anoxia.

    In plain wordsIn rats, cerebrolysin given to mothers during pregnancy increased their young's resistance to oxygen deprivation.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseOffspring resistance to anoxia
    Study

    ratn: not reported in source

    Offspring of rats treated during pregnancy, exposed to anoxia
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Cerebrolysin(R) significantly raised the resistance of the young of females injected ten times i.p. with the same dose during pregnancy.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In 35-day-old rats, repeated (5-fold) cerebrolysin administration significantly increased resistance to anoxia.

    In plain wordsIn young rats, repeated cerebrolysin treatment increased resistance to oxygen deprivation.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseYoung rat resistance to anoxia after repeated administration
    Study

    ratn: not reported in source

    Rats exposed to anoxia
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The repeated (5-fold) administration of Cerebrolysin(R) significantly raised the resistance of 35-day-old rats to anoxia
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In adult rats, repeated cerebrolysin administration at high concentrations increased resistance to anoxia.

    In plain wordsIn adult rats, repeated cerebrolysin at high concentrations increased resistance to oxygen deprivation.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseAdult rat resistance to anoxia at high concentrations
    Study

    ratn: not reported in source

    Rats exposed to anoxia
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The repeated (5-fold) administration of Cerebrolysin(R) significantly raised the resistance of 35-day-old rats to anoxia and, in high concentrations, it also increased the resistance of adult rats.

Studies that did not test the peptide alone1

In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cerebrolysin.

  1. 05AnimalNot a test of Cerebrolysin aloneAnimal study (in vivo)Mechanism

    In rats, cerebrolysin's effect on anoxia resistance correlated with its proportions of amino acids, aligopeptides and nucleotides.

    In plain wordsIn rats, cerebrolysin's effect on oxygen deprivation resistance was linked to its proportions of amino acids, aligopeptides and nucleotides.

    Peptide
    Cerebrolysin
    Outcome
    Direction not reportedComposition-effect correlation
    Study

    ratn: not reported in source

    Rats exposed to anoxia
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    The effect of Cerebrolysin(R) is correlated to the proportion of amino acids, aligopeptides and the nucleotides they contain.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.