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Study · Measured the body's own peptide · 1979

12 results

The distribution of oxytocin- and neurophysin-stained fibers in the spinal cord of the rat and monkey.

Swanson LW, McKellar S

The Journal of comparative neurology1 Nov 1979Cited by 256 (Europe PMC)

PMID115910 (opens in a new tab)DOI10.1002/cne.901880108 (opens in a new tab)PepBankPUB-00115910
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study12

No result from this study comes from a test of the peptide.

Natural levels measured12

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueMechanism

    In albino rats, oxytocin-stained fibers descended through the dorsal lateral funiculus to the caudal spinal cord.

    In plain wordsIn lab tests of rat spinal-cord tissue, the body's own oxytocin-stained fibers ran down the cord to its lower end.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-stained fiber descent in spinal cord
    Study

    ratn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    In albino rats of either sex, such fibers descend through the dorsal part of the lateral funiculus to the caudal end of the cord.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueMechanism

    In albino rats, oxytocin-stained fibers innervated the marginal dorsal horn and the intermediolateral column.

    In plain wordsIn lab tests of rat spinal-cord tissue, the body's own oxytocin-stained fibers reached parts of the dorsal horn and intermediolateral column.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-stained fiber innervation of dorsal horn and intermediolateral column
    Study

    ratn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Fibers leave the lateral funiculus to innervate the marginal zone of the dorsal horn at all levels, and the intermediolateral column at thoracic, lumbar and sacral levels.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueMechanism

    In albino rats, oxytocin-stained fibers appeared to innervate the central gray at all spinal levels.

    In plain wordsIn lab tests of rat spinal-cord tissue, the body's own oxytocin-stained fibers appeared to reach central gray tissue throughout the cord.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-stained fiber innervation of central gray
    Study

    ratn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Some fibers course medially through the intermediate gray to end in the central gray, which is innervated at all levels, and also appears to be innervated by fibers descending in the central gray itself.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelEx vivo tissueMechanism

    In albino rats, terminal-field density of oxytocin-stained fibers varied significantly across spinal levels.

    In plain wordsIn lab tests of rat spinal-cord tissue, the body's own oxytocin-stained terminal-field density differed significantly across spinal levels.

    Peptide
    Oxytocin
    Outcome
    Not applicableTerminal-field density across spinal levels
    Study

    ratn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    A semiquantitative analysis shows that the density of terminal fields in the intermediolateral column, marginal zone, and central gray varies significantly at different levels.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  5. 05LabEndogenous levelEx vivo tissueMechanism

    In albino rats, the intermediolateral column was preferentially innervated by oxytocin-stained fibers at T1-T3, T9-T11, and T13-L2.

    In plain wordsIn lab tests of rat spinal-cord tissue, the body's own oxytocin-stained fibers preferentially innervated specified intermediolateral levels.

    Peptide
    Oxytocin
    Outcome
    Not applicableIntermediolateral column oxytocin-stained fiber density
    Study

    ratn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    The intermediolateral column is preferentially innervated between T1-T3, T9-T11, and T13-L2.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  6. 06LabEndogenous levelEx vivo tissueMechanism

    In albino rats, the nucleus intercalatusspinalis and dorsal commissural nucleus were densely innervated by oxytocin-stained fibers.

    In plain wordsIn lab tests of rat spinal-cord tissue, the body's own oxytocin-stained fibers densely innervated two preganglionic-neuron nuclei.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-stained fiber innervation of preganglionic-neuron nuclei
    Study

    ratn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    The nucleus intercalatusspinalis and the dorsal commissural nucleus (between T13 and L2), both of which contain preganglionic neurons, are densely innervated.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  7. 07LabEndogenous levelEx vivo tissueMechanism

    In monkeys, oxytocin-stained fibers descended through the lateral funiculus to the filum terminale.

    In plain wordsIn lab tests of monkey spinal-cord tissue, the body's own oxytocin-stained fibers ran to the filum terminale.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-stained fiber descent to filum terminale
    Study

    monkeyn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    In the monkey (Macaca fascicularis), neurophysin I- and oxytocin-stained fibers descend through the lateral funiculus to the filum terminale, where some of them enter the pia-arachnoid surrounding the filum.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  8. 08LabEndogenous levelEx vivo tissueMechanism

    In monkeys, oxytocin-stained fibers in the intermediolateral column were absent, sparse, or moderate depending on spinal level, with greatest density at L3.

    In plain wordsIn lab tests of monkey spinal-cord tissue, the body's own oxytocin-stained fiber density in one column varied by level and was greatest at L3.

    Peptide
    Oxytocin
    Outcome
    Not applicableIntermediolateral column oxytocin-stained fiber density
    Study

    monkeyn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    The intermediolateral column is not innervated between T1-T3, is sparsely innervated at sacral levels, and is moderately innervated between T4 and L3; the greatest density of fibers occurs at L3.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  9. 09LabEndogenous levelEx vivo tissueMechanism

    In monkeys, few if any oxytocin-stained fibers were found in central gray at most levels, with sparse innervation at specified levels.

    In plain wordsIn lab tests of monkey spinal-cord tissue, the body's own oxytocin-stained fibers were usually scarce in central gray tissue.

    Peptide
    Oxytocin
    Outcome
    Not applicableCentral-gray oxytocin-stained fiber distribution
    Study

    monkeyn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    At most levels, few if any fibers are found in the central gray and marginal zone; the central gray is sparsely innervated between T8 and L2 at S2, and between Co3-Co6, and the marginal zone contains a small number of fibers in the region of S2 and Co6.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  10. 10LabEndogenous levelEx vivo tissueMechanism

    In Brattleboro, spontaneously hypertensive, and Egyptian sand rats, oxytocin-stained fibers were found in the intermediolateral column, marginal zone, and central gray.

    In plain wordsIn lab tests of several rat strains, the body's own oxytocin-stained fibers were found in three spinal-cord regions.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-stained fibers in additional rat strains
    Study

    rat and Egyptian sand ratn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Neurophysin I- and oxytocin-stained fibers were also found in the intermediolateral column, marginal zone, and central gray of homozygous Brattleboro, spontaneously hypertensive, and Egyptian sand rats.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  11. 11LabEndogenous levelEx vivo tissueMechanism

    In monkeys, some neurophysin I- and oxytocin-stained fibers entered the pia-arachnoid surrounding the filum terminale.

    In plain wordsIn lab tests of monkey spinal-cord tissue, some of the body's own oxytocin-stained fibers entered the pia-arachnoid around the filum terminale.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-stained fiber entry into pia-arachnoid
    Study

    monkeyn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    In the monkey (Macaca fascicularis), neurophysin I- and oxytocin-stained fibers descend through the lateral funiculus to the filum terminale, where some of them enter the pia-arachnoid surrounding the filum.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  12. 12LabEndogenous levelEx vivo tissueMechanism

    In monkeys, few if any oxytocin-stained fibers were found in the marginal zone at most levels, with small numbers near S2 and Co6.

    In plain wordsIn lab tests of monkey spinal-cord tissue, the body's own oxytocin-stained fibers were usually scarce in marginal-zone tissue.

    Peptide
    Oxytocin
    Outcome
    Not applicableMarginal-zone oxytocin-stained fiber distribution
    Study

    monkeyn: not reported in source

    spinal cord
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    At most levels, few if any fibers are found in the central gray and marginal zone; the central gray is sparsely innervated between T8 and L2 at S2, and between Co3-Co6, and the marginal zone contains a small number of fibers in the region of S2 and Co6.
    1 context sentence
    Summary · context
    Immunohistochemical methods have been used to describe the distribution of neurophysin I- and oxytocin-stained fibers in the spinal cord.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 11:11 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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