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Study · Ex vivo tissue · 1978

3 results

Effect of human serum thymic factor on immature T lymphocytes in acute leukemia and other hematologic malignancies.

Cavdar AO, Ozger Topuz U, Erten J, Losio M, Erten M, Astaldi G

Israel journal of medical sciences1 Dec 1978

PMID107146 (opens in a new tab)DOI10.1159/000403133 (opens in a new tab)PepBankPUB-00107146
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In cells from acute leukemia patients, thymic factor increased E-rosette-forming cells in 8 of 37 patients.

    In plain wordsIn lab tests, thymic factor increased E-rosette-forming cells compared with before incubation in 8 of 37 leukemia patients.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseE-rosette formation in acute leukemia
    Study

    humann = 37

    peripheral blood mononuclear cells
    Comparator
    Before incubation with human serum thymic factor
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Measurements

    patients with increased E-rosette formation
    8 patients
    acute leukemia
    patients tested
    37 patients
    acute leukemia

    Source sentences

    Summary
    This assay showed that incubation with thymic factor caused a clear-cut increase of E-rosette-forming cells in 8 of the 37 acute leukemia patients.
    1 context sentence
    Summary · context
    In 37 patients with acute leukemia and in 13 patients with other hematologic malignancies, E-rosette formation of peripheral blood mononuclear cells, before and after incubation with human serum thymic factor, was studied.
  2. 02LabEx vivo tissueActivity measurement

    In cells from patients with other hematologic malignancies, thymic factor increased E-rosette formation in two pediatric Hodgkin's disease patients.

    In plain wordsIn lab tests, thymic factor increased E-rosette formation compared with before incubation in two children with Hodgkin's disease.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseE-rosette formation in pediatric Hodgkin disease
    Study

    humann: not reported in source

    peripheral blood mononuclear cells
    Comparator
    Before incubation with human serum thymic factor
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Among the 13 patients with other hematologic malignancies, a similar effect was observed in two with pediatric Hodgkin's disease and in one adult with Waldenström's macroglobulinemia.
    2 context sentences
    Summary · context
    This assay showed that incubation with thymic factor caused a clear-cut increase of E-rosette-forming cells in 8 of the 37 acute leukemia patients.
    Summary · context
    In 37 patients with acute leukemia and in 13 patients with other hematologic malignancies, E-rosette formation of peripheral blood mononuclear cells, before and after incubation with human serum thymic factor, was studied.
  3. 03LabEx vivo tissueActivity measurement

    In cells from patients with other hematologic malignancies, thymic factor increased E-rosette formation in one adult with Waldenström's macroglobulinemia.

    In plain wordsIn lab tests, thymic factor increased E-rosette formation compared with before incubation in one adult with Waldenström's macroglobulinemia.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseE-rosette formation in Waldenström macroglobulinemia
    Study

    humann: not reported in source

    peripheral blood mononuclear cells
    Comparator
    Before incubation with human serum thymic factor
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Measurements

    patients with increased E-rosette formation
    1 patient
    adult Waldenström's macroglobulinemia

    Source sentences

    Summary
    Among the 13 patients with other hematologic malignancies, a similar effect was observed in two with pediatric Hodgkin's disease and in one adult with Waldenström's macroglobulinemia.
    2 context sentences
    Summary · context
    This assay showed that incubation with thymic factor caused a clear-cut increase of E-rosette-forming cells in 8 of the 37 acute leukemia patients.
    Summary · context
    In 37 patients with acute leukemia and in 13 patients with other hematologic malignancies, E-rosette formation of peripheral blood mononuclear cells, before and after incubation with human serum thymic factor, was studied.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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