Skip to content

Linaclotide clinical trials: 31 trials

Page 1 of 1

Read 31 Linaclotide clinical trials with posted results or linked papers with results in PepBank.

  1. An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation

    NCT00730171 · Phase 3 · Completed

    Posted results

  2. A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

    NCT01880424 · Phase 3 · Completed

    Posted results

  3. An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation

    NCT00765999 · Phase 3 · Completed

    Posted results

  4. Trial of Linaclotide in Patients With Chronic Idiopathic Constipation

    NCT02291679 · Phase 3 · Completed

    Posted results

  5. An Open-Label, Long-term Study to Assess the Immunogenicity of LINZESS® (Linaclotide) Administered Orally to Adult Participants With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation

    NCT02590432 · Phase 4 · Completed

    Posted results

  6. Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

    NCT00938717 · Phase 3 · Completed

    Posted results

  7. Trial of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation

    NCT00948818 · Phase 3 · Completed

    Posted results

  8. Trial of Linaclotide in Patients With Chronic Constipation

    NCT00730015 · Phase 3 · Completed

    Posted results

  9. Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial of Linaclotide Administered to Patients With Chronic Constipation

    NCT00765882 · Phase 3 · Completed

    Posted results

  10. A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

    NCT03573908 · Phase 3 · Completed

    Posted results

  11. Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating

    NCT01642914 · Phase 3 · Completed

    Posted results

  12. Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)

    NCT04026113 · Phase 3 · Completed

    Posted results

  13. Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C

    NCT04166058 · Phase 3 · Completed

    Posted results

  14. A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation

    NCT05652205 · Phase 3 · Completed

    Posted results

  15. A Study of the Effect of Linaclotide on Abdominal Girth in Participants With Irritable Bowel Syndrome With Constipation (IBS-C)

    NCT02837783 · Phase 4 · Terminated

    Posted results

  16. Phase III Study to Evaluate the Efficacy and Safety of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome

    NCT02316899 · Phase 3 · Completed

    Linked paper with results

  17. Efficacy of Linaclotide in Patients With Overlapping Functional Gastrointestinal Disorders

    NCT05134584 · Phase 4 · Status unknown

    Linked paper with results

  18. Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

    NCT02559206 · Phase 2 · Completed

    Posted results

  19. Randomized, Double-blind, Dose-range-finding, Phase 2 Study of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

    NCT00460811 · Phase 2 · Completed

    Posted results

  20. Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation

    NCT00402337 · Phase 2 · Completed

    Posted results

  21. Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

    NCT02270983 · Phase 2 · Completed

    Posted results

  22. A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)

    NCT02559570 · Phase 2 · Completed

    Posted results

  23. A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation

    NCT02559817 · Phase 2 · Terminated

    Posted results

  24. Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation

    NCT04110145 · Phase 2 · Completed

    Posted results

  25. A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide

    NCT05760313 · Phase 2 · Completed

    Posted results

  26. A Study to Evaluate Dose Responses of Efficacy and Safety of ASP0456 in Patient With Chronic Constipation

    NCT02425722 · Phase 2 · Completed

    Linked paper with results

  27. Proof of Principle Study for an Efficacy Trial of Linaclotide for Cystic Fibrosis

    NCT07569419 · Early phase 1 · Recruiting

    Linked paper with results

  28. Efficacy of Linaclotide to Senna for CIC

    NCT02239510 · Not applicable · Terminated

    Posted results

  29. Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy

    NCT05291325 · Not applicable · Completed

    Linked paper with results

  30. Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation

    NCT05137145 · Not applicable · Status unknown

    Linked paper with results

  31. Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients

    NCT02078323 · Not applicable · Completed

    Linked paper with results

How PepBank reports evidence